High-resolution vessel wall imaging for quantitatively and qualitatively evaluating in-stent stenosis of intracranial aneurysms

作者全名：Chen, Ting; Liu, Shushu; Jiang, Yongxiang; Wu, Wei; Li, Jiali; Li, Kunhua; Guo, Dajing

作者地址：[Chen, Ting; Liu, Shushu; Wu, Wei; Li, Jiali; Li, Kunhua; Guo, Dajing] Chongqing Med Univ, Affiliated Hosp 2, Dept Radiol, Chongqing, Peoples R China; [Liu, Shushu] Peoples Hosp Fengjie, Dept Med Imaging, Chongqing, Peoples R China; [Jiang, Yongxiang] Chongqing Med Univ, Affiliated Hosp 2, Dept Neurosurg, Chongqing, Peoples R China

通信作者：Li, KH; Guo, DJ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Radiol, Chongqing, Peoples R China.

来源：FRONTIERS IN NEUROLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001229395900001

JCR分区：Q2

影响因子：2.7

年份：2024

卷号：15

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：stent placement; in-stent stenosis; intracranial aneurysms; high-resolution vessel wall imaging; follow-up

摘要：Background: It is critical to accurately and noninvasively evaluate the stented parent artery of intracranial aneurysms (IAs) with endovascular treatment. Objective To investigate high-resolution vessel wall imaging (HR-VWI) for quantitative and qualitative evaluation of in-stent stenosis (ISS) in IAs treated with stent placement (SP). Methods: Fifty-five patients (58 aneurysms) underwent HR-VWI, contrast-enhanced (CE)-HR-VWI, CE-MR angiography (MRA), time-of-flight (TOF)-MRA, and digital subtraction angiography (DSA) six months after SP, and the reliability of quantitative stent lumen measurements was evaluated by intraclass correlation coefficient (ICC) analysis. Agreement and correlation of quantitative evaluation were estimated by comparing the four MR imaging modalities with DSA. The diagnostic performance for >0%, >= 25%, and >= 50% of ISS degrees and overall diagnostic accuracy for the ISS degrees of the four MR imaging modalities were calculated to qualitative evaluation. Results: The reliability of CE-HR-VWI and HR-VWI for ISS quantitative measurements was excellent (ICC 0.955-0.989). The agreement and correlation of CE-HR-VWI, HR-VWI versus DSA for ISS quantitative measurements were better than those of CE-MRA and TOF-MRA (p < 0.05). The diagnostic performance for distinguishing the degree of ISS >0%, >= 25%, and >= 50% by CE-HR-VWI and HR-VWI was superior to CE-MRA and TOF-MRA, and their overall diagnostic accuracy was 96.55 and 94.83%, respectively. HR-VWI and CE-HR-VWI were not statistically significant in the quantitative and qualitative evaluation of ISS performance (p > 0.05). Conclusion: HR-VWI and CE-HR-VWI have similar performance and value in the quantitative and qualitative evaluation of ISS, and HR-VWI without contrast media could be used as an ideal long-term follow-up approach after SP treatment for IAs.

基金机构：Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) [2024MSXM044]

基金资助正文：The author(s) declare that financial support was received for the research, authorship, and/or publication of this article. This work was supported by Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau), Grant Number: 2024MSXM044.