Anomalous origin of the coronary artery: prevalence and coronary artery disease in adults undergoing coronary tomographic angiography

作者全名：Li, Kunyan; Hu, Ping; Luo, Xiaolin; Li, Furong; Chen, Ling; Zhao, Junyong; Wang, Zelan; Luo, Wenjian; Jin, Jun; Qin, Zhexue

作者地址：[Li, Kunyan; Luo, Xiaolin; Chen, Ling; Zhao, Junyong; Wang, Zelan; Luo, Wenjian; Jin, Jun; Qin, Zhexue] Army Med Univ, Xinqiao Hosp, Dept Cardiol, Chongqing, Peoples R China; [Hu, Ping] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing, Peoples R China; [Li, Furong] Army Med Univ, Xinqiao Hosp, Dept Nephrol, Chongqing, Peoples R China

通信作者：Jin, J; Qin, ZX (通讯作者)，Army Med Univ, Xinqiao Hosp, Dept Cardiol, Chongqing, Peoples R China.

来源：BMC CARDIOVASCULAR DISORDERS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001230259700001

JCR分区：Q3

影响因子：2

年份：2024

卷号：24

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Anomalous aortic origin of coronary artery; Coronary artery disease; Coronary computed tomographic angiography

摘要：Background Anomalous aortic origin of a coronary artery (AAOCA) is a rare congenital coronary anomaly with the potential to cause adverse cardiac events. However, there is limited data on the association between AAOCA and coronary artery disease (CAD). Therefore, the aim of this study is to determine the prevalence and symptoms of patients with AAOCA, as well as investigate the correlation between AAOCA and CAD in a population referred for coronary computed tomographic angiography (CTA).Methods and results All consecutive patients who underwent CTA from 2010 to 2021 were included. Characteristics, symptoms, coronary related adverse events and CTA information were reviewed by medical records. Separate multivariable cumulative logistic regressions were performed, using the stenosis severity in each of the four coronaries as individual responses and as a combined patient clustered response. Finally, we identified 207 adult patients with AAOCA, the prevalence of AAOCA is 0.23% (207/90,501). Moreover, this study found no significant association between AAOCA and CAD. AAOCA did not contribute to higher rates of hospitalization or adverse cardiac events, including calcification.Conclusion AAOCA is a rare congenital disease that is not associated with increased presence of obstructive CAD in adults.

基金机构：Chongqing Key Laboratory of Cardiovascular Disease Research Project

基金资助正文：Not applicable.