"A cross-sectional, multicenter survey of the prevalence and influencing factors for migraine in epilepsy"

作者全名："Shi, Wenyan; Sun, Hanlin; Peng, Wei; Chen, Ziyi; Wang, Qun; Lin, Weihong; Ding, Meiping; Sun, Hongbin; Wang, Xiangqing; Wang, Tiancheng; Wang, Xuefeng; Liu, Yonghong; Chen, Yangmei; Zhu, Guoxing; Zhou, Dong; Li, Jinmei"

作者地址："[Shi, Wenyan; Sun, Hanlin; Peng, Wei; Zhou, Dong; Li, Jinmei] Sichuan Univ, West China Hosp, Dept Neurol, 37 Guoxue Lane, Chengdu 610041, Peoples R China; [Chen, Ziyi] Sun Yat Sen Univ, Affiliated Hosp 1, Dept Neurol, Guangzhou, Peoples R China; [Wang, Qun] Capital Med Univ, Beijing Tiantan Hosp, Dept Neurol, Beijing, Peoples R China; [Lin, Weihong] First Hosp Jilin Univ, Dept Neurol, Changchun, Peoples R China; [Ding, Meiping] Zhejiang Univ, Affiliated Hosp 2, Dept Neurol, Hangzhou, Peoples R China; [Sun, Hongbin] Sichuan Prov Peoples Hosp, Dept Neurol, Chengdu, Peoples R China; [Wang, Xiangqing] Chinese Peoples Liberat Army PLA Gen Hosp, Dept Neurosurg, Beijing, Peoples R China; [Wang, Tiancheng] Lanzhou Univ Second Hosp, Dept Neurol, Lanzhou, Peoples R China; [Wang, Xuefeng] Chongqing Med Univ, Affiliated Hosp 1, Dept Neurol, Chongqing, Peoples R China; [Liu, Yonghong] Air Force Med Univ, Xijing Hosp, Dept Neurol, Xian, Peoples R China; [Chen, Yangmei] Chongqing Med Univ, Affiliated Hosp 2, Dept Neurol, Chongqing, Peoples R China; [Zhu, Guoxing] Fudan Univ, Huashan Hosp, Dept Neurol, Shanghai, Peoples R China"

通信作者："Zhou, D; Li, JM (通讯作者)，Sichuan Univ, West China Hosp, Dept Neurol, 37 Guoxue Lane, Chengdu 610041, Peoples R China."

来源：EPILEPSIA OPEN

ESI学科分类：　

WOS号：WOS:001234719900001

JCR分区：Q2

影响因子：3

年份：2024

卷号：9

期号：4

开始页：1406

结束页：1415

文献类型：Article

关键词：epilepsy; influencing factor; management; migraine

摘要："Objectives: Epilepsy and migraine are common chronic neurological disease. Epidemiologic studies and shared pathophysiology and treatment suggest that these two diseases overlap. However, migraine is often underestimated among patients with epilepsy. This study aimed to evaluate the prevalence of migraine and identify the related influencing factors among adult patients with epilepsy. Methods: Adult patients with epilepsy were recruited at the outpatient epilepsy clinic of 13 tertiary hospitals in China from February to September 2022. ID Migraine questionnaire was applied to evaluate for migraine. Both univariable and multivariable logistic regression models were used to explore the influencing factors of migraine. Results: A total of 1326 patients with epilepsy were enrolled in this study. The prevalence of migraine among patients with epilepsy was 19.2% (254/1326). In the multivariable analysis, being female (OR = 1.451, 95% CI: 1.068-1.975; p = 0.018), focal and focal to bilateral tonic-clonic seizures (OR = 1.583, 95% CI: 1.090-2.281; p = 0.015), and current seizure attack in the last 3 months (OR = 1.967, 95% CI: 1.282-3.063; p = 0.002) were the influencing factors for migraine. However, <10% of patients with epilepsy received analgesics for migraine. Significance: Approximately 20% of patients with epilepsy screened positive for migraine. Being female, focal and focal to bilateral tonic-clonic seizures, and current seizure attack in the last 3 months were the influencing factors for migraine. Neurologists should pay more attention to the screening and management of the migraine among patients with epilepsy in China. Plain Language Summary: Epilepsy and migraine are common chronic neurological disease with shared pathophysiological mechanisms and therapeutic options. However, migraine is often underestimated among patients with epilepsy. This multicenter study aimed to evaluate the prevalence of migraine and current status of treatment. In this study, approximately 20% of patients with epilepsy screened positive for migraine. Female, focal and focal to bilateral tonic-clonic seizures, and current seizure attack in the last 3 months were identified as independent influencing factors for migraine. Despite the high prevalence, the treatment for migraine was not optimistic, neurologists should pay more attention to the screening and management of migraine."

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