Non-coding RNAs and exosomal non-coding RNAs in lung cancer: insights into their functions

作者全名：Lv, Xiaolong; Yang, Lei; Xie, Yunbo; Momeni, Mohammad Reza

作者地址：[Lv, Xiaolong] Peoples Hosp Changshou, Dept Cardiothorac Surg, Chongqing, Peoples R China; [Yang, Lei] Peoples Hosp Tongliang Dist, Dept Cardiothorac Surg, Chongqing, Peoples R China; [Xie, Yunbo] Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiothorac Surg, Chongqing, Peoples R China; [Momeni, Mohammad Reza] Univ Tehran Med Sci, Sch Med, Tehran, Iran

通信作者：Xie, YB (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Cardiothorac Surg, Chongqing, Peoples R China.; Momeni, MR (通讯作者)，Univ Tehran Med Sci, Sch Med, Tehran, Iran.

来源：FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

ESI学科分类：MOLECULAR BIOLOGY & GENETICS

WOS号：WOS:001241286400001

JCR分区：Q1

影响因子：4.6

年份：2024

卷号：12

期号：　

开始页：　

结束页：　

文献类型：Review

关键词：lung cancer; non-coding RNA; microRNA; long non-coding RNA; circular RNA

摘要：Lung cancer is the second most common form of cancer worldwide Research points to the pivotal role of non-coding RNAs (ncRNAs) in controlling and managing the pathology by controlling essential pathways. ncRNAs have all been identified as being either up- or downregulated among individuals suffering from lung cancer thus hinting that they may play a role in either promoting or suppressing the spread of the disease. Several ncRNAs could be effective non-invasive biomarkers to diagnose or even serve as effective treatment options for those with lung cancer, and several molecules have emerged as potential targets of interest. Given that ncRNAs are contained in exosomes and are implicated in the development and progression of the malady. Herein, we have summarized the role of ncRNAs in lung cancer. Moreover, we highlight the role of exosomal ncRNAs in lung cancer.

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