3D MR neurography with gadolinium contrast to improve the visualization of pelvic nerves and the branches

作者全名：Liu, Hui; Xiao, Zhibo; Tao, Li; Tang, Mingmei; Xu, Yong; Pan, Yuanrui; Zhang, Ke; Qiu, Xueke; Lv, Fajin

作者地址：[Liu, Hui; Tang, Mingmei; Pan, Yuanrui; Zhang, Ke; Qiu, Xueke; Lv, Fajin] Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China; [Xiao, Zhibo; Tao, Li; Xu, Yong; Lv, Fajin] Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, Chongqing, Peoples R China

通信作者：Lv, FJ (通讯作者)，Chongqing Med Univ, Coll Biomed Engn, State Key Lab Ultrasound Med & Engn, Chongqing, Peoples R China.; Lv, FJ (通讯作者)，Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, Chongqing, Peoples R China.

来源：FRONTIERS IN PHYSIOLOGY

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:001242994800001

JCR分区：Q2

影响因子：3.2

年份：2024

卷号：15

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：magnetic resonance neurography; pelvic nerve; gadolinium; signal-to-noise ratio; contrast-to-noise ratio; contrast ratio

摘要：Objective: To evaluate the effectiveness of 3D NerveVIEW sequence with gadolinium contrast on the visualization of pelvic nerves and their branches compared to that without contrast. Methods: Participants were scanned twice using 3D NerveVIEW sequence with and without gadolinium contrast to acquire pelvic nerve images. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and contrast ratio of the nerves were calculated and compared to determine the quality of images. To subjectively assess, using a 3-point scale, branch nerves critical to therapeutic decision-making, including the pelvic splanchnic nerve and pelvic plexus, the superior gluteal nerve, and the pudendal nerve. Results: In the 32 eligible participants after using contrast, the CNRs of the images of nerve-to-bone and nerve-to-vessel significantly increased (p < 0.05). The CR of the images with contrast of all nerve-to-surrounding tissues (i.e., bone, muscle, blood vessels, and fat) were also found significantly higher (p < 0.05). The assessment of observers also shows higher scores for images with contrast compared to images without contrast. Conclusion: The 3D NerveVIEW sequence combined with gadolinium contrast improved vascular suppression, increased the contrast between pelvic nerves and surrounding tissue, and enhanced the visualization of nerves and their branches. This study may be helpful for the technically challenging preoperative planning of pelvic diseases surgery.

基金机构：Foundation of State Key Laboratory of Ultrasound in Medicine and Engineering [2022KFKT005]

基金资助正文：We thank all the staff at the Radiology Department of The First Affiliated Hospital of Chongqing Medical University in Chongqing, China for their work.r The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by Foundation of State Key Laboratory of Ultrasound in Medicine and Engineering (Grant No.2022KFKT005).