Awareness about Neonatal Lactose Intolerance among Chinese Neonatologists in Outpatient Settings: A Multi-Center Survey

作者全名："Wang, Zhengli; Liu, Liting; Yu, Chao; Tang, Wenyan; Ding, Xiangping; Hu, Xiangwen; Shi, Yuan"

作者地址："[Wang, Zhengli; Liu, Liting; Shi, Yuan] Chongqing Med Univ, Dept Neonatol, Childrens Hosp, Chongqing 400014, Peoples R China; [Wang, Zhengli; Liu, Liting; Shi, Yuan] Natl Clin Res Ctr Child Hlth & Disorders, Chongqing 400014, Peoples R China; [Wang, Zhengli; Liu, Liting; Shi, Yuan] Minist Educ, Key Lab Child Dev & Disorders, Chongqing 400014, Peoples R China; [Wang, Zhengli; Liu, Liting; Shi, Yuan] Chongqing Key Lab Child Rare Dis Infect & Immun, Chongqing 400014, Peoples R China; [Wang, Zhengli; Tang, Wenyan; Ding, Xiangping; Hu, Xiangwen; Shi, Yuan] Chongqing Med Univ, Jiangxi Hosp, Childrens Hosp, Nanchang 330000, Peoples R China; [Yu, Chao] Chongqing Med & Pharmaceut Coll, Affiliated Hosp 1, Chongqing 400016, Peoples R China"

通信作者："Shi, Y (通讯作者)，Chongqing Med Univ, Dept Neonatol, Childrens Hosp, Chongqing 400014, Peoples R China.; Shi, Y (通讯作者)，Natl Clin Res Ctr Child Hlth & Disorders, Chongqing 400014, Peoples R China.; Shi, Y (通讯作者)，Minist Educ, Key Lab Child Dev & Disorders, Chongqing 400014, Peoples R China.; Shi, Y (通讯作者)，Chongqing Key Lab Child Rare Dis Infect & Immun, Chongqing 400014, Peoples R China.; Shi, Y (通讯作者)，Chongqing Med Univ, Jiangxi Hosp, Childrens Hosp, Nanchang 330000, Peoples R China."

来源：CHILDREN-BASEL

ESI学科分类：　

WOS号：WOS:001304969300001

JCR分区：Q2

影响因子：2.4

年份：2024

卷号：11

期号：8

开始页：　

结束页：　

文献类型：Article

关键词：awareness; neonatal lactose intolerance; neonatologists

摘要："Background: This study aimed to identify the specific areas of knowledge gaps regarding lactose intolerance among neonatologists in Chinese outpatient settings as well as to assess the availability of lactose intolerance testing in hospitals. Methods: A total of 278 neonatologists in outpatient settings from 144 hospitals were surveyed. To explore the awareness level, diagnosis, and treatment of neonatal lactose intolerance among neonatologists in outpatient settings, a multicenter cross-sectional survey was designed. Descriptive analysis based on frequency and percent distribution was performed for all variables. Results: Most respondents were senior doctors (256, 92.09%) from general hospitals and maternity/maternal and child health hospitals, had over 10 years of experience, and were dominantly associate chief physicians and chief physicians (211, 75.90%). A significant proportion of the participants (236, 84.89%) believed that neonatal lactose intolerance tends to be overlooked during clinical practice. When the most common symptoms of neonatal lactose intolerance were surveyed, diarrhea was selected by 142 (51.08%) respondents, followed by bloating and milk regurgitation or emesis (71, 25.54%). Other symptoms included unexplained crying (36, 12.85%), stool with milk flap or foam (15, 5.40%), and increased venting (14, 5.04%). Furthermore, the survey results indicated that the most common method for diagnosing neonatal lactose intolerance in the respondents' hospitals was qualitative test for urinary galactose (78, 28.06%). Of the respondents, 137 (49.28%) stated that their hospital could not test for lactose intolerance. For treating lactose intolerance, the neonatologists primarily opted for exogenous lactase rather than lactose-free formula milk. Conclusions: This study sheds light on Chinese neonatologists' awareness of neonatal lactose intolerance, revealing some knowledge gaps. The expeditious popularization and conduct of lactose intolerance-related examinations in hospitals will have a positive stimulative effect on the management of lactose intolerance in newborns."

基金机构：the National Key Research and Development Program of China [2022YFC2704803]; National Key Research and Development Program of China [CSTC2021jscx-gksb-N0015]; Technical Innovation and promotion project of Chongqing

基金资助正文："This research was funded by the National Key Research and Development Program of China, grant number 2022YFC2704803, Technical Innovation and promotion project of Chongqing, grant number CSTC2021jscx-gksb-N0015."