Comparison of visual quality after wavefront-guided LASIK in patients with different levels of preoperative total ocular higher-order aberrations: a retrospective study

作者全名："Zhang, Yu; Du, Yangrui; He, Ming; Zhang, Youdan; Du, Zhiyu"

作者地址："[Zhang, Yu; Du, Yangrui; He, Ming; Zhang, Youdan; Du, Zhiyu] Chongqing Med Univ, Affiliated Hosp 2, Dept Ophthalmol, Chongqing, Peoples R China; [Zhang, Yu; Du, Yangrui] Medal Eye Inst, Chongqing, Peoples R China"

通信作者："Du, ZY (通讯作者)，Chongqing Med Univ, Affiliated Hosp 2, Dept Ophthalmol, Chongqing, Peoples R China."

来源：PEERJ

ESI学科分类：Multidisciplinary

WOS号：WOS:001335973200006

JCR分区：Q2

影响因子：2.7

年份：2024

卷号：12

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Wavefront-guided; FS-LASIK; Higher-order aberrations; Visual quality; Contrast sensitivity

摘要："Purpose: To compare the visual quality after wavefront-guided femtosecond LASIK (WFG FS-LASIK) in patients with different levels of preoperative total ocular higher-order aberrations to guide clinical decision-making regarding patient selection and treatment strategies. Methods: This study included 112 right eyes of 112 patients who previously underwent WFG FS-LASIK for correcting myopia and myopic astigmatism. The patients were divided into two groups based on the mean values of preoperative total ocular HOAs (0.30 +/- 0.09 mu m): HOA <= 0.3 and > 0.3 groups. The visual acuity, manifest refraction, corneal Strehl ratio (SR), root mean square (RMS) of corneal and ocular aberrations, and area under the log contrast sensitivity function (AULCSF) of both groups were compared preoperatively and at 1, 3, 6, and 12 months postoperatively. Results: The induced ocular HOAs and coma (Delta = 1mo - Preop) were significantly lower in the HOAs > 0.3 group than in the HOAs <= 0.3 group (Delta HOAs: 0.39 +/- 0.19 vs. 0.29 +/- 0.18 mu m, t = 2.797, P = 0.006; Delta coma: 0.30 +/- 0.19 vs. 0.20 +/- 0.21 mm, t = 2.542, P = 0.012). In the HOAs > 0.3 group, Delta HOAs were negatively correlated with the preoperative ocular HOAs (r = -0.315, P = 0.019). In the HOAs <= 0.3 group, the regression equation for Delta HOAs = 0.098 + 0.053 vertical bar SE vertical bar (F = 21.756, P < 0.001). In the HOAs > 0.3 group, the regression equation for Delta HOAs = 0.534 - 1.081 HOAs + 0.038 vertical bar Sphere vertical bar (F = 7.954, P = 0.001). The postoperative uncorrected distance visual acuity, spherical equivalent, corneal aberrations, SR and AULCSF of both groups were similar (all P > 0.05). Furthermore, the ocular aberrations were not significantly different between both groups at 3, 6, and 12 months postoperatively (all P > 0.05). In addition, compared with the preoperative period, the AULCSF of both groups were significantly increased in the postoperative period (all P < 0.05). Conclusions: The induced ocular HOAs and coma in HOAs > 0.3 group were lower. However, both groups achieved equivalent and excellent visual quality after WFG FS-LASIK. WFG FS-LASIK may provide significant visual benefits for a wider range of patients."

基金机构：Key Program of Chongqing Natural Science Foundation; China [cstc2021ycjh-bgzxm0064]

基金资助正文："This work was funded by the Key Program of Chongqing Natural Science Foundation. China (No. cstc2021ycjh-bgzxm0064). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."