Gender and age differences in the association between sleep characteristics and fasting glucose levels in Chinese adults

作者全名："Zheng, R.; Niu, J.; Wu, S.; Wang, T.; Wang, S.; Xu, M.; Chen, Y.; Dai, M.; Zhang, D.; Yu, X.; Tang, X.; Hu, R.; Ye, Z.; Shi, L.; Su, Q.; Yan, L.; Qin, G.; Wan, Q.; Chen, G.; Gao, Z.; Wang, G.; Shen, F.; Luo, Z.; Qin, Y.; Chen, L.; Huo, Y.; Li, Q.; Zhang, Y.; Liu, C.; Wang, Y.; Yang, T.; Deng, H.; Zhao, J.; Mu, Y.; Xu, Y.; Li, M.; Lu, J.; Wang, W.; Zhao, Z.; Bi, Y.; Ning, G."

作者地址："[Zheng, R.; Niu, J.; Wu, S.; Wang, T.; Wang, S.; Xu, M.; Chen, Y.; Dai, M.; Xu, Y.; Li, M.; Lu, J.; Wang, W.; Zhao, Z.; Bi, Y.; Ning, G.] Shanghai Jiao Tong Univ, Sch Med,Shanghai Natl Clin Res Ctr Metab Dis, Shanghai Inst Endocrine & Metab Dis,Ruijin Hosp, Key Lab Endocrine & Metab Dis,Natl Hlth Commiss C, 197 Ruijin 2nd Rd, Shanghai 200025, Peoples R China; [Yu, X.] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Wuhan, Peoples R China; [Tang, X.] Lanzhou Univ, Hosp 1, Lanzhou, Peoples R China; [Hu, R.; Ye, Z.] Zhejiang Prov Ctr Dis Control & Prevent, Hangzhou, Zhejiang, Peoples R China; [Shi, L.] Guiyang Med Coll, Affiliated Hosp, Guiyang, Peoples R China; [Su, Q.] Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Shanghai, Peoples R China; [Yan, L.] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou, Peoples R China; [Qin, G.] Zhengzhou Univ, Affiliated Hosp 1, Zhengzhou, Peoples R China; [Wan, Q.] Luzhou Med Coll, Affiliated Hosp, Luzhou, Peoples R China; [Chen, G.] Fujian Med Univ, Fujian Prov Hosp, Fuzhou, Peoples R China; [Gao, Z.] Dalian Med Univ, Dalian Municipal Cent Hosp, Dalian, Peoples R China; [Wang, G.] First Hosp Jilin Univ, Changchun, Peoples R China; [Shen, F.] Wenzhou Med Univ, Affiliated Hosp 1, Wenzhou, Peoples R China; [Luo, Z.; Qin, Y.] Guangxi Med Univ, Affiliated Hosp 1, Nanning, Peoples R China; [Chen, L.] Shandong Univ, Qilu Hosp, Jinan, Peoples R China; [Huo, Y.] Nanchang Univ, PJiangxi Prov Peoples Hosp, Nanchang, Jiangxi, Peoples R China; [Li, Q.] Harbin Med Univ, Affiliated Hosp 2, Harbin, Peoples R China; [Zhang, Y.] Cent Hosp Shanghai Jiading Dist, Shanghai, Peoples R China; [Liu, C.] Jiangsu Prov Hosp Integrat Chinese & Western Med, Nanjing, Peoples R China; [Wang, Y.] Anhui Med Univ, Affiliated Hosp 1, Hefei, Peoples R China; [Wu, S.] Karamay Municipal Peoples Hosp, Karamay, Xinjiang, Peoples R China; [Yang, T.] Nanjing Med Univ, Affiliated Hosp 1, Nanjing, Peoples R China; [Deng, H.] Chongqing Med Univ, Affiliated Hosp 1, Chongqing, Peoples R China; [Chen, L.] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Wuhan, Peoples R China; [Zhao, J.] Shandong Univ, Shandong Prov Hosp, Jinan, Peoples R China; [Mu, Y.] Chinese Peoples Liberat Army Gen Hosp, Beijing, Peoples R China; [Zhang, D.; Xu, Y.] Shanghai Jiao Tong Univ, Ruijin Hosp, Clin Trials Ctr, Sch Med, Shanghai, Peoples R China"

通信作者："Xu, Y; Zhao, Z; Bi, Y (corresponding author), Shanghai Jiao Tong Univ, Sch Med,Shanghai Natl Clin Res Ctr Metab Dis, Shanghai Inst Endocrine & Metab Dis,Ruijin Hosp, Key Lab Endocrine & Metab Dis,Natl Hlth Commiss C, 197 Ruijin 2nd Rd, Shanghai 200025, Peoples R China."

来源：DIABETES & METABOLISM

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:000629307600004

JCR分区：Q1

影响因子：7.2

年份：2021

卷号：47

期号：2

开始页：　

结束页：　

文献类型：Article

关键词：Fasting glucose; Hyperglycaemia; Sleep duration

摘要："Aim. - The present study examined the associations between night-time sleep duration, midday napping duration and bedtime, and fasting glucose levels, and whether or not such associations are dependent on gender and age. Methods. - This study was a cross-sectional analysis of 172,901 adults aged >= 40 years living in mainland China. Sleep duration was obtained by self-reports of bedtime at night, waking-up time the next morning and average napping duration at midday. Fasting plasma glucose (FPG) >= 7.0 mmol/L was defined as hyperglycaemia. Independent associations between night-time sleep duration, midday naptime duration and bedtime with hyperglycaemia were evaluated using regression models. Results. - Compared with night-time sleep durations of 6-7.9 h, both short (< 6 h) and long (>= 8 h) night-time sleep durations were significantly associated with an increased risk of hyperglycaemia in women [odds ratio (OR): 1.12, 95% confidence interval (CI): 1.01-1.29 and OR: 1.14, 95% CI: 1.08-1.21, respectively], and revealed a U-shaped distribution of risk in women and no significant association in men. Long midday nap durations (>= 1 h) were significantly but weakly associated with hyperglycaemia (OR: 1.04, 95% CI: 1.01-1.09) compared with no napping without interactions from gender or age, whereas the association between bedtime and fasting glucose levels did vary according to gender and age. Conclusion. - Night-time sleep duration, midday napping duration and bedtime were all independently associated with the risk of hyperglycaemia, and some of the associations between these sleep characteristics and hyperglycaemia were gender- and age-dependent. (C) 2020 Elsevier Masson SAS. All rights reserved."

基金机构："National Key R&D Program of China [2017YFC1310700, 2016YFC1305600, 2018YFC1311800, 2016YFC0901200, 2016YFC1305202, 2016YFC1304904]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81870560, 81700764, 81561128019]; National Science and Technology Major Project for ""Significant New Drugs Development'' [2017ZX09304007]; Shanghai Municipal Government [18411951800]; Shanghai Shenkang Hospital Development Centre [SHDC12019101]; Shanghai Jiaotong University School of Medicine [DLY201801]; Shanghai Outstanding Academic Leader Program; Outstanding Young Talent Program from Shanghai Municipal Government; Ruijin Hospital [2018CR002]"

基金资助正文："This work was supported by grants from the National Key R&D Program of China (2017YFC1310700, 2016YFC1305600, 2018YFC1311800, 2016YFC0901200, 2016YFC1305202, 2016YFC1304904), National Natural Science Foundation of China (81870560, 81700764, 81561128019), National Science and Technology Major Project for ``Significant New Drugs Development'' (2017ZX09304007), Shanghai Municipal Government (18411951800), Shanghai Shenkang Hospital Development Centre (SHDC12019101), Shanghai Jiaotong University School of Medicine (DLY201801) and Ruijin Hospital (2018CR002). Dr Y. Bi was supported by the Shanghai Outstanding Academic Leader Program, and Dr Y. Xu was supported by the Outstanding Young Talent Program from Shanghai Municipal Government."