Expert consensus of the Chinese Association for the Study of Pain on ion channel drugs for neuropathic pain

作者全名："Xiao, Hong; Ma, Ke; Huang, Dong; Liu, Xian-Guo; Liu, Tang-Hua; Liu, Qing; Liu, Guang-Zhao; Song, Tao; Tao, Wei; Wu, Da-Sheng; Wang, Yun-Xia; Yang, Xiao-Qiu; Zhang, Xiao-Mei; Liu, Hui; Liu, Yan-Qing"

作者地址："[Xiao, Hong; Liu, Hui] Sichuan Univ, West China Hosp, Dept Algol, 37 Guo Xue Xiang, Chengdu 610041, Sichuan, Peoples R China; [Ma, Ke] Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Dept Algol, Shanghai 200092, Peoples R China; [Huang, Dong] Cent South Univ, Dept Algol, Xiangya Hosp 3, Changsha 410013, Hunan, Peoples R China; [Liu, Xian-Guo] Sun Yat Sen Univ, Dept Physiol, Guangzhou 510080, Guangdong, Peoples R China; [Liu, Xian-Guo] Sun Yat Sen Univ, Pain Res Ctr, Guangzhou 510080, Guangdong, Peoples R China; [Liu, Tang-Hua] Third Peoples Hosp Yibin, Dept Algol, Yibin 644000, Sichuan, Peoples R China; [Liu, Qing] Southwest Med Univ, Affiliated TCM Hosp, Dept Algol, Luzhou 646000, Sichuan, Peoples R China; [Liu, Guang-Zhao] Hebei Med Univ, Hosp 2, Dept Algol, Shijiazhuang 050000, Hebei, Peoples R China; [Song, Tao] China Med Univ, Affiliated Hosp 1, Dept Algol, Shenyang 110001, Liaoning, Peoples R China; [Tao, Wei] Shenzhen Univ, Dept Neurosurg, Gen Hosp, Shenzhen 518055, Guangdong, Peoples R China; [Wu, Da-Sheng] Peoples Hosp Jilin Prov, Dept Algol, Changchun 130021, Jilin, Peoples R China; [Wang, Yun-Xia] Jianghan Univ, Dept Algol, Hubei Peoples Hosp 3, Wuhan 430033, Hubei, Peoples R China; [Yang, Xiao-Qiu] Chongqing Med Univ, Affiliated Hosp 1, Dept Algol, Chongqing 400016, Peoples R China; [Zhang, Xiao-Mei] Kunming Med Univ, Affiliated Hosp 1, Dept Algol, Kunming 650032, Yunnan, Peoples R China; [Liu, Yan-Qing] Capital Med Univ, Dept Algol, Beijing Tiantan Hosp, Beijing 100070, Peoples R China"

通信作者："Liu, H (corresponding author), Sichuan Univ, West China Hosp, Dept Algol, 37 Guo Xue Xiang, Chengdu 610041, Sichuan, Peoples R China."

来源：WORLD JOURNAL OF CLINICAL CASES

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000637814400009

JCR分区：Q3

影响因子：1.1

年份：2021

卷号：9

期号：9

开始页：2100

结束页：2109

文献类型：Article

关键词：Ion channel drug; Neuropathic pain; Expert consensus; Guideline; Gabapentin; Carbamazepine; Oxcarbazepine; Lidocaine; Bulleyaconitine A; Pregabalin

摘要："Neuropathic pain (NPP) is a kind of pain caused by disease or damage impacting the somatosensory system. Ion channel drugs are the main treatment for NPP; however, their irregular usage leads to unsatisfactory pain relief. To regulate the treatment of NPP with ion channel drugs in clinical practice, the Chinese Association for the Study of Pain organized first-line pain management experts from China to write an expert consensus as the reference for the use of ion channels drugs . Here, we reviewed the mechanism and characteristics of sodium and calcium channel drugs, and developed recommendations for the therapeutic principles and clinical practice for carbamazepine, oxcarbazepine, lidocaine, bulleyaconitine A, pregabalin, and gabapentin. We hope this guideline provides guidance to clinicians and patients on the use of ion channel drugs for the management of NPP."

基金机构：Sichuan Science and Technology Program [2018SZ0386]

基金资助正文："Supported by Sichuan Science and Technology Program, No. 2018SZ0386"