Expert consensus of the Chinese Association for the Study of Pain on pain treatment with the transdermal patch

作者全名："Ma, Ke; Jiang, Wei; Wang, Yun-Xia; Wang, Lin; Lv, Yan; Liu, Jin-Feng; Liu, Rong-Guo; Liu, Hui; Xiao, Li-Zu; Du, Dong-Ping; Lu, Li-Juan; Yang, Xiao-Qiu; Xia, Ling-Jie; Huang, Dong; Fu, Zhi-Jian; Peng, Bao-Gan; Liu, Yan-Qing"

作者地址："[Ma, Ke] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Algol, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China; [Jiang, Wei] Peoples Liberat Army Gen Hosp, Med Ctr 3, Dept Anesthesiol, Beijing 100039, Peoples R China; [Wang, Yun-Xia] Hubei Zhongshan Hosp, Peoples Hosp Hubei Prov 3, Dept Algol, Wuhan 430033, Hubei, Peoples R China; [Wang, Lin] Guizhou Med Univ, Dept Algol, Affiliated Hosp, Guiyang 550004, Guizhou, Peoples R China; [Lv, Yan] Air Force Med Univ, Xijing Hosp, Dept Algol, Xian 710032, Shaanxi, Peoples R China; [Liu, Jin-Feng] Harbin Med Univ, Affiliated Hosp 2, Dept Algol, Harbin 150001, Heilongjiang, Peoples R China; [Liu, Rong-Guo] Fujian Prov Hosp, Dept Algol, Fuzhou 350001, Fujian, Peoples R China; [Liu, Hui] Sichuan Univ, Dept Algol, West China Hosp, Chengdu 610041, Sichuan, Peoples R China; [Xiao, Li-Zu] Nanshan Hosp, Shenzhen Peoples Hosp 6, Dept Algol, Shenzhen 518000, Guangdong, Peoples R China; [Du, Dong-Ping] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 6, Dept Algol, Shanghai 200233, Peoples R China; [Lu, Li-Juan] Nanjing Univ, Med Sch, Affiliated Hosp, Dept Algol,Nanjing Drum Tower Hosp, Nanjing 210008, Jiangsu, Peoples R China; [Yang, Xiao-Qiu] Chongqing Med Univ, Affiliated Hosp 1, Dept Algol, Chongqing 400016, Peoples R China; [Xia, Ling-Jie] Henan Prov Peoples Hosp, Dept Algol, Zhengzhou 450000, Henan, Peoples R China; [Huang, Dong] Cent South Univ, Dept Algol, Xiangya Hosp 3, Changsha 410013, Hunan, Peoples R China; [Fu, Zhi-Jian] Shandong Univ, Dept Algol, Shandong Prov Hosp, Jinan 250021, Shandong, Peoples R China; [Peng, Bao-Gan] Gen Hosp Chinese Peoples Liberat Army, Med Ctr 3, Dept Orthoped, Beijing 100039, Peoples R China; [Liu, Yan-Qing] Capital Med Univ, Beijing Tiantan Hosp, Dept Algol, Beijing 100050, Peoples R China"

通信作者："Ma, K (corresponding author), Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Dept Algol, 1665 Kongjiang Rd, Shanghai 200092, Peoples R China."

来源：WORLD JOURNAL OF CLINICAL CASES

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000637814400010

JCR分区：Q3

影响因子：1.1

年份：2021

卷号：9

期号：9

开始页：2110

结束页：2122

文献类型：Article

关键词：Transdermal drug delivery systems; Pain; Transdermal patches; Topical; Nonsteroidal anti-inflammatory drugs; Analgesics

摘要："Chronic pain lasting more than 3 mo, or even several years can lead to disability. Treating chronic pain safely and effectively is a critical challenge faced by clinicians. Because administration of analgesics through oral, intravenous or intramuscular routes is not satisfactory, research toward percutaneous delivery has gained interest. The transdermal patch is one such percutaneous delivery system that can deliver drugs through the skin and capillaries at a certain rate to achieve a systemic or local therapeutic effect in the affected area. It has many advantages including ease of administration and hepatic first pass metabolism avoidance as well as controlling drug delivery, which reduces the dose frequency and side effects. If not required, then the patch can be removed from the skin immediately. The scopolamine patch was the first transdermal patch to be approved for the treatment of motion sickness by the Food and Drug Administration in 1979. From then on, the transdermal patch has been widely used to treat many diseases. To date, no guidelines or consensus are available on the use of analgesic drugs through transdermal delivery. The pain branch of the Chinese Medical Association, after meeting and discussing with experts and based on clinical evidence, developed a consensus for promoting and regulating standard use of transdermal patches containing analgesic drugs."

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