High prevalence of osteoporosis in patients undergoing spine surgery in China

作者全名："Mo, Xiaoyi; Zhao, Shengli; Wen, Zhenxing; Lin, Wei; Chen, Zhipeng; Wang, Zhiyun; Huang, Chen; Qin, Jie; Hao, Jie; Chen, Bailing"

作者地址："[Mo, Xiaoyi; Zhao, Shengli; Wen, Zhenxing; Lin, Wei; Chen, Zhipeng; Chen, Bailing] Sun Yat Sen Univ, Dept Spine Surg, Affiliated Hosp 1, Guangzhou, Peoples R China; [Mo, Xiaoyi; Zhao, Shengli; Wen, Zhenxing; Lin, Wei; Chen, Zhipeng; Chen, Bailing] Guangdong Prov Key Lab Orthopaed & Traumatol, Guangzhou, Peoples R China; [Wang, Zhiyun] Southern Med Univ, Dept Spine Surg, Shunde Hosp, Foshan, Peoples R China; [Huang, Chen] Yantai Mt Hosp, Dept Orthopaed, Yantai, Shandong, Peoples R China; [Qin, Jie; Hao, Jie] Chongqing Med Univ, Affiliated Hosp 1, Dept Spine Surg, Chongqing, Peoples R China"

通信作者："Chen, BL (corresponding author), Sun Yat Sen Univ, Dept Spine Surg, Affiliated Hosp 1, Guangzhou, Peoples R China.; Chen, BL (corresponding author), Guangdong Prov Key Lab Orthopaed & Traumatol, Guangzhou, Peoples R China."

来源：BMC GERIATRICS

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000661237600001

JCR分区：Q1

影响因子：4.1

年份：2021

卷号：21

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Osteoporosis; Prevalence; Spine surgery; Vertebral fracture; Chinese

摘要："Background With the increase in life expectancy, a large number of patients with osteoporosis (OP) are undergoing spine surgery, which may adversely affect the surgical success rate. The prevalence of OP varies in different regions, and no data are available that represent the prevalence of OP among Chinese patients over 50 years of age who are undergoing spine surgery. It was the first multicenter study to assess OP in these patients. Aiming to obtain comprehensive data, this study combined bone mineral density (BMD) measurements and visual radiography assessment (VRA) to analyze the prevalence of OP in patients aged > 50 years who underwent spine surgery. Methods Data from 1,856 patients aged over 50 years undergoing spine surgery who resided in northern, central, and southern China were reviewed between 2018 and 2019. Based on the perioperative BMD and X-ray data, we calculated the prevalence of OP in this special population according to sex, age, and spine degenerative disease. Results A total of 1,245 patients (678 females and 567 males) were included in the study. The prevalence of OP diagnosed by BMD was 52.8 % in females and 18.7 % in males. When we combined with BMD and VRA, the prevalence of OP increased from 52.8 to 65.9 % in females and from 18.7 to 40.6 % in males. Although OP was more severe in females than in males, a significant difference in the rate of vertebral fracture (VF) was not observed between females and males with a normal BMD and osteopenia (females vs. males: aged 50-59 years, P = 0.977; 60-69 years, P = 0.302; >70 years, P = 0.172). Similarly, no significant difference in the vertebral fracture rate was observed within different age groups of patients with a normal BMD and osteopenia (females: P = 0.210; males, P = 0.895). The incidence of OP in patients with degenerative scoliosis was higher than that in the remaining patients (females: 63.6 % vs. 42.4 %, P = 0.018; males: 38.9 % vs. 13.8 %, P = 0.004). Conclusions A high prevalence of OP was identified in patients aged > 50 years undergoing spine surgery, especially in patients whose primary diagnosis was degenerative scoliosis. BMD and VRA evaluations should be included in the clinical routine for these patients prior to surgery."

基金机构："Natural Science Foundation of chinaNational Natural Science Foundation of China (NSFC) [31570976]; Science and Technology Program of Guangzhou, china [201604020148]"

基金资助正文："This study was supported by the Natural Science Foundation of china (no. 31570976), and the Science and Technology Program of Guangzhou, china (no. 201604020148). The content is solely the responsibility of the authors and does not represent any official views."