The psychological impact on patients with memory disorders and their caregivers during COVID-19

作者全名："Yuan, Shiyun; Zhang, Wenbo; Lu, Wenqi; Yu, Wuhan; Zhong, Fuxin; Xiong, Lei; Wan, Tianchi; Hu, Cheng; Yang, Wenkai; Chen, Chenxi; Luo, Daijing; Tan, Binjie; Huang, Chengcheng; Yu, Weihua; Lu, Yang"

作者地址："[Yuan, Shiyun; Zhang, Wenbo; Yu, Wuhan; Xiong, Lei; Wan, Tianchi; Hu, Cheng; Yang, Wenkai; Chen, Chenxi; Huang, Chengcheng; Lu, Yang] Chongqing Med Univ, Dept Geriatr, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Zhong, Fuxin; Yu, Weihua] Chongqing Med Univ, Inst Neurosci, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China; [Lu, Wenqi; Luo, Daijing; Tan, Binjie] Chongqing Med Univ, Chongqing, Peoples R China"

通信作者："Lu, Y (corresponding author), Chongqing Med Univ, Dept Geriatr, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China.; Yu, WH (corresponding author), Chongqing Med Univ, Inst Neurosci, 1 Yixueyuan Rd, Chongqing 400016, Peoples R China."

来源：AGING CLINICAL AND EXPERIMENTAL RESEARCH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000664415500002

JCR分区：Q2

影响因子：4

年份：2021

卷号：33

期号：8

开始页：2317

结束页：2325

文献类型：Article

关键词：COVID-19; Psychological impact; Memory disorders; The elderly; Caregiver

摘要："Background COVID-19 is erupting globally. Mass quarantine had been implemented all around China which could influence the psychological status of patients with memory disorders and their caregivers. Aim To investigate the psychological impact of mass quarantine on patients with memory disorders and their caregivers in China. Methods We completed a cross-sectional study in 787 patients and their caregivers registered from 2010 to 2019 in Memory Clinic, The First Affiliated Hospital of Chongqing Medical University, by telephone interviews. The performance in neuropsychiatric symptoms (NPSs), sleep, nutrition, chronic diseases of patients, and the burden of care, anxiety and depression of caregivers was assessed by six assessment scales (MNA-SF, PSQI, NPI, RSS, PHQ-9 and GAD-7). Results Only 68 (8.6%) patients worried about the outbreak of COVID-19. The prevalence of NPSs among all subjects was nearly 60.0%. Approximately 50.0% of the caregivers reported distress. More than 70.0% of patients remained stable in NPSs. However, anxiety, depression, aberrant motor disorder and delusion were exacerbated (22.9%, 18.6%, 17.1% and 16.8%, respectively). Appetite and eating disorder led alleviation rate by 25.8% while disappearing rate of agitation led by 5.8%. 7.5% of caregivers manifested depressive symptoms while 4.9% expressed anxiety symptoms, and 40.8% showed care burden. The coefficients of RSS and PHQ-9, RSS and GAD-7, RSS and NPI-D, PHQ-9 and GAD-7 were 0.7, 0.5, 0.5 and 0.6, respectively (p < 0.01). Conclusion Changes in NPSs during COVID-19 were observed in some patients with memory disorders and their caregivers, and adherence to medication contributed to the stabilization of NPSs."

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