Association of education levels with the risk of hypertension and hypertension control: a nationwide cohort study in Chinese adults

作者全名："Sun, Kan; Lin, Diaozhu; Li, Mian; Mu, Yiming; Zhao, Jiajun; Liu, Chao; Bi, Yufang; Chen, Lulu; Shi, Lixin; Li, Qiang; Yang, Tao; Wan, Qin; Wu, Shengli; Wang, Guixia; Luo, Zuojie; Qin, Yingfen; Tang, Xulei; Chen, Gang; Huo, Yanan; Gao, Zhengnan; Su, Qing; Ye, Zhen; Hu, Ruying; Wang, Youmin; Qin, Guijun; Deng, Huacong; Yu, Xuefeng; Shen, Feixia; Chen, Li; Wang, Weiqing; Ning, Guang; Yan, Li"

作者地址："[Sun, Kan] Sun Yat Sen Univ, Dept Endocrinol, Guangzhou, Peoples R China; [Lin, Diaozhu; Yan, Li] Sun Yat Sen Mem Hosp, Dept Endocrinol, Guangzhou, Guangdong, Peoples R China; [Li, Mian; Bi, Yufang] Shanghai Jiao Tong Univ, Med Sch, Affiliated Ruijin Hosp, Shanghai, Peoples R China; [Mu, Yiming] Chinese Peoples Liberat Army Gen Hosp, Dept Endocrinol, Beijing, Peoples R China; [Zhao, Jiajun] Shandong Prov Hosp, Dept Endocrinol, Jinan, Shandong, Peoples R China; [Liu, Chao] Jiangsu Prov Hosp Integrat Chinese & Western Med, Nanjing, Jiangsu, Peoples R China; [Chen, Lulu] Hua Zhong Univ Sci & Technol, Union Hosp, Tong Ji Med Coll, Wuhan, Peoples R China; [Shi, Lixin] Guiyang Med Coll, Affiliated Hosp, Guiyang, Peoples R China; [Li, Qiang] Harbin Med Univ, Affiliated Hosp 2, Harbin, Peoples R China; [Yang, Tao] Jiangsu Prov Hosp, Nanjing, Jiangsu, Peoples R China; [Yang, Tao] Nanjing Med Univ, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China; [Wan, Qin] Luzhou Med Coll, Affiliated Hosp, Luzhou, Peoples R China; [Wu, Shengli] Karamay Municipal Peoples Hosp, Karamay, Xinjiang, Peoples R China; [Wang, Guixia] Jilin Univ, Hosp 1, Dept Endocrinol, Changchun, Jilin, Peoples R China; [Luo, Zuojie; Qin, Yingfen] Guangxi Med Univ, Affiliated Hosp 1, Dept Endocrinol, Nanning, Guangxi, Peoples R China; [Tang, Xulei] Lanzhou Univ, Affiliated Hosp 1, Dept Endocrinol, Lanzhou, Gansu, Peoples R China; [Chen, Gang] Fujian Prov Hosp, Dept Endocrinol, Fuzhou, Fujian, Peoples R China; [Huo, Yanan] Jiangxi Prov Peoples Hosp, Dept Endocrinol, Nanchang, Jiangxi, Peoples R China; [Gao, Zhengnan] Ctr Hosp Dalian, Dept Endocrinol, Dalian, Peoples R China; [Su, Qing] Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Dept Endocrinol, Shanghai, Peoples R China; [Ye, Zhen; Hu, Ruying] Zhejiang Prov Ctr Dis Control & Prevent, Hangzhou, Zhejiang, Peoples R China; [Wang, Youmin] Anhui Med Univ, Affiliated Hosp 1, Dept Endocrinol, Hefei, Peoples R China; [Qin, Guijun] Zhengzhou Univ, Affiliated Hosp 1, Dept Endocrinol, Zhengzhou, Henan, Peoples R China; [Deng, Huacong] Chongqing Med Univ, Affiliated Hosp 1, Dept Endocrinol, Chongqing, Sichuan, Peoples R China; [Yu, Xuefeng] Huazhong Univ Sci & Technol, Dept Endocrinol, Wuhan, Peoples R China; [Shen, Feixia] Wenzhou Med Univ, Affiliated Hosp 1, Dept Endocrinol, Wenzhou, Zhejiang, Peoples R China; [Chen, Li] Shandong Univ, Qilu Hosp, Dept Endocrinol, Jinan, Shandong, Peoples R China; [Wang, Weiqing; Ning, Guang] Shanghai Jiao Tong Univ, Shanghai Natl Res Ctr Endocrine & Metab Dis, Shanghai Inst Endocrine & Metab Dis,Med Sch, Dept Endocrinol,Ruijin Hosp,State Key Lab Med Ge, Shanghai, Peoples R China"

通信作者："Yan, L (通讯作者)，Sun Yat Sen Mem Hosp, Dept Endocrinol, Guangzhou, Guangdong, Peoples R China."

来源：JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

ESI学科分类：SOCIAL SCIENCES, GENERAL

WOS号：WOS:000741024800001

JCR分区：Q1

影响因子：6.3

年份：2022

卷号：76

期号：5

开始页：451

结束页：457

文献类型：Article

关键词：hypertension; education; cohort studies

摘要："Background Education attainment can improve life expectancy and guide healthy behaviours throughout an entire lifetime. A nationwide longitudinal study of the association of education status with the risk of hypertension and its control in China is lacking. Methods The China Cardiometabolic Disease and Cancer Cohort Study is a multicentre, population-based, prospective cohort study. We performed the baseline survey from 2011 to 2012. A follow-up visit was conducted during 2014-2016. 101 959 subjects were included in the final data analyses. Cox proportional hazards regression was used to examine the associations of education levels with the risk of hypertension and uncontrolled hypertension. Results During follow-up, 11 189 (19.9%) participants had developed hypertension among subjects without hypertension at baseline. Among the participants with hypertension at baseline, only 40.6% had controlled hypertension. Compared with the participants' education level at elementary school and below, the multivariable-adjusted HR for incident hypertension was 0.76 (95% CI, 0.72 to 0.80) in those with a middle school education level and 0.67 (95% CI, 0.63 to 0.70) in those with a high school degree or above. Correspondingly, multivariable-adjusted HRs associated with uncontrolled hypertension were 0.90 (95% CI, 0.87 to 0.92) in participants with a middle school education level and 0.85 (95% CI, 0.82 to 0.88) in participants with a high school degree or above level. Conclusion Participants with education attainment at elementary school and below exhibited excess risks of newly diagnosed hypertension and worse blood pressure control compared with individuals with education attainment at middle school or above."

基金机构："National Key R&D Program of China [2016YFC0901204, 2016YFC1305600, 2016YFC1305202, 2016YFC1304904, 2017YFC1310700, 2018YFC1311705, 2018YFC1311800]; National Natural Science Foundation of China [81970696]; Sun Yat-sen Clinical Research Cultivating Program [SYS-Q-201801]; Sun Yat-sen University Clinical Research 5010 Program [2018021]; Science and Technology Planning Project of Guangdong Province, China [2014A020212069]; Medical Scientific Research Foundation of Guangdong Province, China [C2019106]"

基金资助正文："This work was supported by grants from the following: (1) National Key R&D Program of China (Nos.2016YFC0901204, 2016YFC1305600, 2016YFC1305202, 2016YFC1304904, 2017YFC1310700, 2018YFC1311705, and 2018YFC1311800); (2) The National Natural Science Foundation of China (81970696); (3) Sun Yat--sen Clinical Research Cultivating Program (SYS--Q--201801); and (4) Sun Yat--sen University Clinical Research 5010 Program (2018021); (5) Science and Technology Planning Project of Guangdong Province, China (2014A020212069); (6) Medical Scientific Research Foundation of Guangdong Province, China (C2019106). These funding associations had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript."