Associations of PM2.5 and road traffic noise with mental health: Evidence from UK Biobank

作者全名："Hao, Guang; Zuo, Lei; Xiong, Peng; Chen, Li; Liang, Xiaohua; Jing, Chunxia"

作者地址："[Hao, Guang; Zuo, Lei; Jing, Chunxia] Jinan Univ, Sch Med, Dept Epidemiol, 601 West Huangpu Rd, Guangzhou 510632, Guangdong, Peoples R China; [Hao, Guang; Jing, Chunxia] Jinan Univ, Guangdong Key Lab Environm Exposure & Hlth, Guangzhou, Peoples R China; [Xiong, Peng] Jinan Univ, Sch Med, Dept Publ Hlth & Prevent Med, Div Med Psychol & Behav Sci, Guangzhou, Peoples R China; [Chen, Li] Augusta Univ, Med Coll Georgia, Georgia Prevent Inst, Dept Populat Hlth Sci, Augusta, GA USA; [Liang, Xiaohua] Chongqing Med Univ, Childrens Hosp,Clin Epidemiol & Biostat Dept,Mini, Natl Clin Res Ctr Child Hlth & Disorders,Key Lab, China Int Sci & Technol Cooperat Ctr Child Dev &, 136 2nd St, Chongqing 400014, Peoples R China"

通信作者："Hao, G; Jing, CX (通讯作者)，Jinan Univ, Sch Med, Dept Epidemiol, 601 West Huangpu Rd, Guangzhou 510632, Guangdong, Peoples R China.; Liang, XH (通讯作者)，Chongqing Med Univ, Childrens Hosp,Clin Epidemiol & Biostat Dept,Mini, Natl Clin Res Ctr Child Hlth & Disorders,Key Lab, China Int Sci & Technol Cooperat Ctr Child Dev &, 136 2nd St, Chongqing 400014, Peoples R China."

来源：ENVIRONMENTAL RESEARCH

ESI学科分类：ENVIRONMENT/ECOLOGY

WOS号：WOS:000751896000001

JCR分区：Q1

影响因子：8.3

年份：2022

卷号：207

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Air pollution; Road traffic noise; Depression; Anxiety; Stress; Bipolar disorder

摘要："Background: The associations of atmospheric particulate matter with diameters of 2.5 mu m or less (PM2.5) and road traffic noise with mental disorders in men and women are not well studied. Objectives: We aim to examine the cross-sectional associations of PM2.5 and road traffic noise with mental disorders in men and women. Methods: The baseline data of the UK Biobank study (2006-2010) were used. Mental disorders including symptoms of nerves, anxiety, tension or depression (NATD), major depression, and bipolar disorder were assessed by validated questions. Verified models were used to estimate PM2.5 and road traffic noise. Results: A total of 334,986 participants with measurements of NATD and 90,706 participants with measurements of major depression and bipolar disorder were included in the analysis. After adjusting for covariates, the odds for the risk of NATD symptoms increased by 2.31 (95% CI: 2.15-2.50) times per 10 mu g/m3 increase in PM2.5. The odds for the risk of major depression and bipolar disorder increased by 2.26 and 4.99 times per 10 mu g/m3 increase in PM2.5. On the other hand, higher road traffic noise exposure was significantly associated with a higher risk of NATD symptoms (Decile 6-8 (54.9-57.8 dB), OR: 1.03, 95% CI: 1.01-1.06; Decile 9-10 (>57.8 dB), OR: 1.04, 95% CI: 1.01-1.07) and bipolar disorder (Decile 2-5 (52.1-54.9 dB), OR: 1.26, 95% CI: 1.00-1.59; Decile 6-8 (54.9-57.8 dB), OR: 1.30, 95% CI: 1.02-1.65; Decile 9-10 (>57.8 dB), OR: 1.54, 95% CI: 1.21-1.97). Interestingly, a negative association was observed between moderate road traffic noise and major depression (Decile 2-5 (52.1-54.9 dB), OR: 0.95, 95% CI: 0.90-1.00). Interactions between PM2.5 exposure with age, gender, and sleeplessness for NATD symptoms were observed (P < 0.05), while interactions between road traffic noise exposure with age and gender were observed (P < 0.05). Conclusions: We found a positive association between PM2.5 and mental disorders. Meanwhile, we found a positive association of road traffic noise with NATD symptoms and bipolar disorder and a negative association of moderate road traffic noise with major depression. Also, the effect modifications of these associations by age, gender, or sleeplessness may exist."

基金机构：Fundamental Research Funds for the Central Universities [21619332]

基金资助正文：This study was supported by the Fundamental Research Funds for the Central Universities (21619332) .