"Association of self-reported snoring and hyperuricaemia: a large cross-sectional study in Chongqing, China"

作者全名："Chen, Ting; Ding, Xianbin; Tang, Wenge; Chen, Liling; Mao, Deqiang; Song, Lingling; Lian, Xuemei"

作者地址："[Chen, Ting; Song, Lingling; Lian, Xuemei] Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China; [Chen, Ting; Ding, Xianbin; Tang, Wenge; Chen, Liling; Mao, Deqiang] Chongqing Ctr Dis Control & Prevent, Dept Noncommunicable Dis Control & Prevent, Chongqing, Peoples R China"

通信作者："Lian, XM (通讯作者)，Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China."

来源：BMJ OPEN

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000778054700002

JCR分区：Q1

影响因子：2.9

年份：2022

卷号：12

期号：4

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Objective To examine the relationship between self-reported snoring and hyperuricaernia in a large-scale population in Chongqing, China. Setting Face-to-face electronic questionnaire survey, physical examination and biological sample testing were conducted in 13 districts of Chongqing. Chongqing is a municipality in southwest China. Participants In this study, 23 308 Han ethnicity permanent residents aged 30-79 years were recruited. Individuals missing data were excluded, 22 389 subjects were included in final analysis. Primary and secondary outcome measures Serum uric acid (UA) was measured using an oxidase method. Hyperuricaemia was defined as serum UA >420 mu mol/L in men and >360 mu mol/L in women. Information about self-reported snoring was obtained by questionnaire survey. M participants were divided into 'no snoring""snoring occasionally' and 'snoring frequently'. Multivariable logistic regression analysis was performed to assess the relationship between selfreported snoring and hyperuricaemia. Results The prevalence of hyperuricaemia was 14.43%, and snorers were more likely to have hyperuricaemia than non-snorer in different age and gender groups. For the total population, those who snore occasionally or frequently were more likely to be hyperuricaemia (OR 1.19, 95% CI 1.07 to 1.31; OR 1.33, 95% C11.19 to 1.47) compared with no snoring people. Stratification by age, gender and body mass index (BMI), we found that the positive association between snoring frequently and hyperuricaemia was insisted in different age, gender and high BMI groups, and the strength of association varied with different age, gender and BMI category. Conclusion Snoring frequency was positively associated with higher risk of hyperuricaernia. Snoring frequently may be a signal for hyperuricaernia, especially for women, those over 59 years of age, or those who are overweight or obese."

基金机构：National Key R&D Program of China [2017YFC0907303]; Chongqing medical scientific research project [2020FYYX013]

基金资助正文：This work was supported by National Key R&D Program of China (grant number: 2017YFC0907303) and Chongqing medical scientific research project (grant number: 2020FYYX013).