Relapsing cellulitis associated with Campylobacter coli bacteremia in a Good's syndrome patient: a case report

作者全名："Jiang, Lei; Gao, Jia; Wang, Pu; Liu, Yuliang"

作者地址："[Jiang, Lei; Wang, Pu; Liu, Yuliang] Chongqing Med Univ, Dept Resp Med, Affiliated Hosp 1, Chongqing, Peoples R China; [Gao, Jia] Chongqing Med Univ, Dept Radiol, Affiliated Hosp 1, Chongqing, Peoples R China"

通信作者："Liu, YL (通讯作者)，Chongqing Med Univ, Dept Resp Med, Affiliated Hosp 1, Chongqing, Peoples R China."

来源：BMC INFECTIOUS DISEASES

ESI学科分类：IMMUNOLOGY

WOS号：WOS:000779812100004

JCR分区：Q2

影响因子：3.7

年份：2022

卷号：22

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Campylobacter coli; Bacteremia; Cellulitis; Case report

摘要："Background Good's syndrome (GS) is characterized by immunodeficiency, and patients diagnosed with GS are susceptible to infection or even bacteremia, which is the most evident complication. Campylobacter coli (C. coli) rarely causes bacteremia or extraintestinal infection. We report herein a case with GS in which right leg cellulitis associated with C. coli bacteremia occurred three times over one and a half years. Case presentation A 41-year-old Chinese male with GS was diagnosed with C. coli infection. He presented with swelling and redness of right lower leg and developed bacteremia due to C. coli repeatedly. Bacteremia was confirmed by bacteriological examination. Adding long-term oral antibiotic treatment with amoxicillin/clavulanate potassium and gentamicin following intravenous meropenem and amikacin was very effective. The blood cultures became negative and the patient has been free from any symptoms encountered for more than one year without relapse of bacteremia. Conclusions Patients with GS and their physicians should carefully consider the antibacterial treatment options against C. coli bacteremia. Combined anti-infective therapy involving aminoglycoside is preferred in the treatment of C. coli bacteremia in GS patients."

基金机构：In-hospital Cultivation Fund of the First Affiliated Hospital of Chongqing Medical University [PYJJ2019-207]; Young and Middle-aged High-end Talents Project of the First Affiliated Hospital of Chongqing Medical University [2022GDRC010]

基金资助正文："This work was supported by the In-hospital Cultivation Fund of the First Affiliated Hospital of Chongqing Medical University (Grant No. PYJJ2019-207) and Young and Middle-aged High-end Talents Project of the First Affiliated Hospital of Chongqing Medical University (Grant No. 2022GDRC010). The funding bodies had no role in the study design, data collection and analysis, interpretation of data, and writing the manuscript."