Ratiometric Monitoring of Biogenic Amines by a Simple Ammonia-Response Aiegen

作者全名："Guo, Xujing; Chen, Xirui; Chen, Rui; Tu, Yujie; Lu, Tianying; Guo, Yuqian; Guo, Liang; Xiong, Yonghua; Huang, Xiaolin; Tang, Ben Zhong"

作者地址："[Guo, Xujing; Chen, Xirui; Lu, Tianying; Guo, Yuqian; Xiong, Yonghua; Huang, Xiaolin] Nanchang Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Nanchang 330031, Jiangxi, Peoples R China; [Guo, Xujing; Guo, Liang; Xiong, Yonghua] Nanchang Univ, Jiangxi OAI Joint Res Inst, Nanchang 330047, Jiangxi, Peoples R China; [Chen, Rui] Chongqing Med Univ, Coll Lab Med, Minist Educ, Key Lab Clin Lab Diagnost, Chongqing 400016, Peoples R China; [Tu, Yujie; Tang, Ben Zhong] AIE Inst, Guangzhou 510530, Peoples R China; [Tang, Ben Zhong] Chinese Univ Hong Kong, Shenzhen Inst Aggregate Sci & Technol, Sch Sci & Engn, Shenzhen 518172, Peoples R China"

通信作者："Huang, XL (通讯作者)，Nanchang Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Nanchang 330031, Jiangxi, Peoples R China.; Chen, R (通讯作者)，Chongqing Med Univ, Coll Lab Med, Minist Educ, Key Lab Clin Lab Diagnost, Chongqing 400016, Peoples R China."

来源：FOODS

ESI学科分类：AGRICULTURAL SCIENCES

WOS号：WOS:000781927700001

JCR分区：Q1

影响因子：5.2

年份：2022

卷号：11

期号：7

开始页：　

结束页：　

文献类型：Article

关键词：aggregation-induced emission; fluorescent sensor; paper chip; biogenic amines; food spoilage

摘要："Herein, we developed a paper-based smart sensing chip for the real-time, visual, and non-destructive monitoring of food freshness using a ratiometric aggregation-induced emission (AIE) luminogen (i.e., H(+)MQ, protonated 4-(triphenylamine)styryl)quinoxalin-2(1H)-one) as pH sensitive indicators. Upon exposure to amine vapors, the deprotonation of H(+)MQ occurs and triggers its color change from blue to yellow, with the fluorescence redshift from blue to amaranth. Consequently, we successfully achieved the sensitive detection of ammonia vapors by recording the bimodal color and fluorescence changes. Given the high sensitivity of H(+)MQ to ammonia vapor, a paper-based smart sensor chip was prepared by depositing H(+)MQ on the commercial qualitative filter paper through a physical deposition strategy. After being placed inside the sealed containers, the developed H(+)MQ-loaded paper chip was applied to the real-time monitoring of biogenic amine contents according to its color difference and ratio fluorescence change. The detection results were further compared with those obtained by the high-performance liquid chromatography method, which verified the feasibility of the designed paper chip for the food spoilage degree evaluation. Briefly, this work indicates that the designed H(+)MQ-loaded paper chip could be a promising approach for improving food freshness monitoring."

基金机构："National Key Research and Development Program of China [2018YFC1602202]; National Natural Science Foundation, China [32172296, 31901780]"

基金资助正文："This research was funded by the National Key Research and Development Program of China (project nos. 2018YFC1602202), and the National Natural Science Foundation, China (project nos. 32172296 and 31901780)."