"Natural source, bioactivity and synthesis of 3-Arylcoumarin derivatives"

作者全名："Zhang, Qiang; Miao, Yu-Hang; Liu, Teng; Yun, Yin-Ling; Sun, Xiao-Ya; Yang, Tao; Sun, Jie"

作者地址："[Zhang, Qiang; Miao, Yu-Hang; Liu, Teng; Yun, Yin-Ling; Sun, Xiao-Ya; Sun, Jie] Shandong First Med Univ, Shandong Acad Med Sci, Inst Mat Med, Jinan 250000, Shandong, Peoples R China; [Yang, Tao] Chongqing Med Univ, Dept Thorac & Cardiovasc Surg, Affiliated Hosp 1, Chongqing 410010, Peoples R China"

通信作者："Sun, J (通讯作者)，Shandong First Med Univ, Shandong Acad Med Sci, Inst Mat Med, Jinan 250000, Shandong, Peoples R China.; Yang, T (通讯作者)，Chongqing Med Univ, Dept Thorac & Cardiovasc Surg, Affiliated Hosp 1, Chongqing 410010, Peoples R China."

来源：JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

ESI学科分类：BIOLOGY & BIOCHEMISTRY

WOS号：WOS:000784658800001

JCR分区：Q1

影响因子：5.6

年份：2022

卷号：37

期号：1

开始页：1023

结束页：1042

文献类型：Review

关键词：Natural product sources; 3-arylcoumarin derivatives; bioactivity; synthesis

摘要："3-arylcoumarins with different pharmacological properties widely exist in a variety of natural plants. The extensive research on 3-arylcoumarins was attributed to its therapeutic and relatively easy isolation. Therefore, 3-arylcoumarins can be recognised as useful structures for the design of novel compounds with potential pharmacological interest, particularly in the fields of anti-inflammatory, anti-cancer, antioxidant, Monoamine oxidase (MAO) enzyme inhibition, etc. The current review highlights the biological activities, design, and chemical synthetic methods of 3-arylcoumarins derivatives as well as their important natural product sources."

基金机构：Shandong Provincial Natural Science Foundation [ZR2020kH020]; academic promotion program of Shandong First Medical University [2019LJ003]

基金资助正文：This work was financially supported by Shandong Provincial Natural Science Foundation [ZR2020kH020]. and the academic promotion program of Shandong First Medical University (nos.2019LJ003).