Cu(OAc)(2) mediated mild synthesis of 2-aminobenzimidazoles and 2-aminobenzoxazoles

作者全名："Han, Lei; Gan, LinLing; Hu, Xiangnan; Li, Wei; Zhu, Dali; Zheng, Jiecheng; Wu, Yue; Yu, Yu; Gan, Zongjie"

作者地址："[Han, Lei; Hu, Xiangnan; Li, Wei; Zhu, Dali; Zheng, Jiecheng; Wu, Yue; Yu, Yu; Gan, Zongjie] Chongqing Med Univ, Coll Pharm, Dept Med Chem, Chongqing, Peoples R China; [Gan, LinLing] Chongqing Med & Pharmaceut Coll, Chongqing Engn Res Ctr Pharmaceut Sci, Sch Pharm, Chongqing, Peoples R China"

通信作者："Yu, Y; Gan, ZJ (通讯作者)，Chongqing Med Univ, Coll Pharm, Dept Med Chem, Chongqing, Peoples R China."

来源：SYNTHETIC COMMUNICATIONS

ESI学科分类：CHEMISTRY

WOS号：WOS:000785905900001

JCR分区：Q3

影响因子：2.1

年份：2022

卷号：52

期号：7

开始页：1050

结束页：1058

文献类型：Article

关键词：2-Aminobenzimidazoles and 2-aminobenzoxazoles; Cu(OAc)(2); desulfurization

摘要："An efficient and facile synthesis for 2-aminobenzimidazoles and 2-aminobenzoxazoles has been reported. Thioureas prepared from the reaction of o-phenylenediamines or 2-aminophenols and isothiocyanate derivatives, underwent desulfurization reaction smoothly under mild conditions in the presence of Cu(OAc)(2), and afforded a variety of N-heterocyclic compounds in moderate to good yields."

基金机构：National Natural Science Foundation of China [21907013]; Scientific and Technological Research Program of Chongqing Municipal Education Commission [KJQN201900431]

基金资助正文：We appreciate the financial support from the National Natural Science Foundation of China [No. 21907013] and the Scientific and Technological Research Program of Chongqing Municipal Education Commission [KJQN201900431].