Effect of enhanced recovery after surgery on inflammatory bowel disease surgery: A meta-analysis

作者全名："Peng, Dong; Cheng, Yu-Xi; Tao, Wei; Tang, Hua; Ji, Guang-Yan"

作者地址："[Peng, Dong; Cheng, Yu-Xi; Tao, Wei; Tang, Hua; Ji, Guang-Yan] Chongqing Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Ji, GY (通讯作者)，Chongqing Med Univ, Dept Gastrointestinal Surg, Affiliated Hosp 1, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：WORLD JOURNAL OF CLINICAL CASES

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000793515400009

JCR分区：Q3

影响因子：1.1

年份：2022

卷号：10

期号：11

开始页：3426

结束页：3435

文献类型：Article

关键词：Enhanced recovery after surgery; Inflammatory bowel disease; Meta-analysis

摘要："BACKGROUND The purpose of enhanced recovery after surgery (ERAS) was to reduce surgical pressure and accelerate postoperative functional recovery. Although the application of biologics in treating inflammatory bowel disease (IBD) has changed treatment strategies, most patients with IBD still require surgery. AIM To evaluate the advantage of ERAS in IBD surgery. METHODS The PubMed, EMBASE and Cochrane Library databases were searched from inception to March 21, 2021 to find eligible studies. The primary outcome was postoperative complications, and the secondary outcomes included operation time, time to first flatus, time to bowel movement, postoperative hospital stay and readmission. The PROSPERO registration ID of this meta-analysis is CRD42021238052. RESULTS A total of eight studies involving 1939 patients were included in this meta-analysis. There were no differences in baseline information between the ERAS group and the non-ERAS group. After pooling up all of the data, no significant difference was found between the ERAS group and the non-ERAS group in terms of postoperative overall complications [odds ratio = 0.82, 95% confidence interval (CI) = 0.66 to 1.02, P = 0.08]. The ERAS group had a lower prevalence of anastomotic fistula (odds ratio = 0.36, 95%CI = 0.13 to 0.95, P = 0.04), less time to first flatus [mean difference (MD) = -2.03, 95%CI = -3.89 to -0.17, P = 0.03], less time to bowel movement (MD = -1.08, 95%CI = -1.60 to -0.57, P < 0.01) and shorter postoperative hospital stays (MD = -1.99, 95%CI = -3.27 to -0.71, P < 0.01) than the non-ERAS group. CONCLUSION ERAS was effective for the quicker recovery in IBD surgery and did not lead to increased complications."

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