Alterations in Fetal Doppler Parameters Before and Twenty-Four Hours After Radiofrequency Ablation for Twin Reversed Arterial Perfusion Sequence

作者全名："Zhang, Lan; Liu, Hongli; Huang, Shuai; Tong, Chao; Wang, Zhigang; Qi, Hongbo; Baker, Philip N.; Kilby, Mark D."

作者地址："[Zhang, Lan; Liu, Hongli; Huang, Shuai; Tong, Chao; Qi, Hongbo] Chongqing Med Univ, State Key Lab Maternal & Fetal Med Chongqing Munic, Affiliated Hosp 1, Chongqing, Peoples R China; [Zhang, Lan; Liu, Hongli; Huang, Shuai; Tong, Chao; Qi, Hongbo] Chongqing Med Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Chongqing, Peoples R China; [Zhang, Lan; Liu, Hongli; Huang, Shuai; Qi, Hongbo] Chongqing Med Univ, Fetal Med Unit, Affiliated Hosp 1, Chongqing, Peoples R China; [Zhang, Lan; Liu, Hongli; Huang, Shuai; Tong, Chao; Qi, Hongbo] Chongqing Med Univ, Int Collaborat Joint Lab Reprod & Dev, Minist Educ PRC, Chongqing, Peoples R China; [Wang, Zhigang] Chongqing Med Univ, Inst Ultrasound Imaging, Dept Ultrasound, Chongqing Key Lab Ultrasound Mol Imaging,Affiliate, Chongqing, Peoples R China; [Baker, Philip N.] Univ Leicester, Coll Life Sci, Leicester, England; [Kilby, Mark D.] Univ Birmingham, Inst Metab & Syst Res, Birmingham, England"

通信作者："Tong, C; Qi, HB (通讯作者)，Chongqing Med Univ, State Key Lab Maternal & Fetal Med Chongqing Munic, Affiliated Hosp 1, Chongqing, Peoples R China.; Tong, C; Qi, HB (通讯作者)，Chongqing Med Univ, Dept Obstet & Gynecol, Affiliated Hosp 1, Chongqing, Peoples R China.; Qi, HB (通讯作者)，Chongqing Med Univ, Fetal Med Unit, Affiliated Hosp 1, Chongqing, Peoples R China.; Tong, C; Qi, HB (通讯作者)，Chongqing Med Univ, Int Collaborat Joint Lab Reprod & Dev, Minist Educ PRC, Chongqing, Peoples R China.; Wang, ZG (通讯作者)，Chongqing Med Univ, Inst Ultrasound Imaging, Dept Ultrasound, Chongqing Key Lab Ultrasound Mol Imaging,Affiliate, Chongqing, Peoples R China."

来源：FRONTIERS IN MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000795461100001

JCR分区：Q1

影响因子：3.9

年份：2022

卷号：9

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：middle cerebral artery; umbilical artery; doppler; twin reversed artery perfusion sequence; radiofrequency ablation; monochorionic twin

摘要："ObjectiveTo evaluate alterations in the fetal Doppler parameters of pump fetuses before and 24 h after radiofrequency ablation surgery for twin reversed arterial perfusion sequence (TRAPs). MethodsThis is a retrospective study of 28 pump fetuses in TRAPs and 28 normal control twins between 2016 and 2021. The fetal Doppler parameters, including the umbilical artery pulsatility index (UA-PI), middle cerebral artery peak systolic velocity (MCA-PSV), middle cerebral artery pulsatility index (MCA-PI), and cerebroplacental ratio (CPR), of the controls, and pump fetuses before and 24 h after surgery were compared. ResultsAn increasing trend and a further increase in the MCA-PSV, MCA-PI, MCA-PSV Z score, and MCA-PI Z score after surgery were observed in pump fetuses with gestational age (GA) >= 20 weeks; however, such changes were not observed in those with a GA of <20 weeks. The UA-PI and CPR before and after surgery were not different between control and pump fetuses, whether the GA was >= 20 or ConclusionIn the middle second trimester, the pump fetus might suffer from high cardiac output rather than hypoxemia before surgery and congestive heart failure, or hemodilutional anemia after surgery. This may provide some theoretical evidence in favor of early intervention, rather than waiting for a more advanced GA, to avoid unnecessary hemodynamic alterations."

基金机构："National Natural Science Foundation of China [U21A20346, 82171662, 82001580]; Chongqing Science and Technology Commission [cstc2021ycjh-bgzxm0192]; Chongqing Health Committee [2019GDRC012, 2021MSXM193]; Chongqing Education Committee [KJZD-K202100404]"

基金资助正文："Funding This study was funded by the National Natural Science Foundation of China (U21A20346, 82171662, and 82001580), Chongqing Science and Technology Commission (cstc2021ycjh-bgzxm0192), Chongqing Health Committee (2019GDRC012 and 2021MSXM193), and Chongqing Education Committee (KJZD-K202100404)."