Does Preoperative Waiting Time Affect the Short-Term Outcomes and Prognosis of Colorectal Cancer Patients? A Retrospective Study from the West of China

作者全名："Liu, Xiao-Yu; Li, Zi-Wei; Kang, Bing; Cheng, Yu-Xi; Tao, Wei; Zhang, Bin; Zhang, Hua; Wei, Zheng-Qiang; Peng, Dong"

作者地址："[Liu, Xiao-Yu; Li, Zi-Wei; Cheng, Yu-Xi; Tao, Wei; Zhang, Bin; Zhang, Hua; Wei, Zheng-Qiang; Peng, Dong] First Affiliated Hosp Chongqing Med Univ, Dept Gastrointestinal Surg, Chongqing 400016, Peoples R China; [Kang, Bing] First Affiliated Hosp Chongqing Med Univ, Dept Clin Nutr, Chongqing 400016, Peoples R China"

通信作者："Peng, D (通讯作者)，First Affiliated Hosp Chongqing Med Univ, Dept Gastrointestinal Surg, Chongqing 400016, Peoples R China."

来源：CANADIAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000796910500001

JCR分区：Q3

影响因子：2.7

年份：2022

卷号：2022

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Purpose. The purpose of this study is to analyze the effect of preoperative waiting time on the short-term outcomes and prognosis in colorectal cancer (CRC) patients. Methods. We retrospectively analyzed 3744 CRC patients who underwent primary CRC surgery at a single clinical medical center from Jan 2011 to Jan 2020. The baseline information, short-term outcomes, overall survival (OS), and disease-free survival (DFS) were compared among the short-waiting group, the intermediate-waiting group, and the long-waiting group. Results. A total of 3744 eligible CRC patients were enrolled for analysis. There were no significant differences in all of the baseline information and short-term outcomes among the three groups. In multivariate analysis, older age (OS: p=0.000, HR = 1.947, 95% CI = 1.631-2.324; DFS: p=0.000, HR = 1.693, 95% CI = 1.445-1.983), advanced clinical stage (OS: p=0.000, HR = 1.301, 95% CI = 1.161-1.457; DFS: p=0.000, HR = 1.262, 95% CI = 1.139-1.400), overall complications (OS: p=0.000, HR = 1.613, 95% CI = 1.303-1.895; DFS: p=0.000, HR = 1.560, 95% CI = 1.312-1.855), and major complications (OS: p=0.001, HR = 1.812, 95% CI = 1.338-2.945; DFS: p=0.006, HR = 1.647, 95% CI = 1.153-2.352) were independent factors of OS and DFS. In addition, no significant difference was found in all stages (OS, p=0.203; DFS, p=0.108), stage I (OS, p=0.419; DFS, p=0.579), stage II (OS, p=0.465; DFS, p=0.385), or stage III (OS, p=0.539; DFS, p=0.259) in terms of OS and DFS among the three groups. Conclusion. Preoperative waiting time did not affect the short-term outcomes or prognosis in CRC patients."

基金机构：Chongqing Key Diseases Research and Application Demonstration Program (Colorectal Cancer Prevention and Treatment Technology Research and Application Demonstration) [2019ZX003]

基金资助正文：The authors acknowledge all the authors whose publications are referred in this article. This study was supported by the Chongqing Key Diseases Research and Application Demonstration Program (Colorectal Cancer Prevention and Treatment Technology Research and Application Demonstration (No. 2019ZX003)).