Fast exhaustive enrichment and electrochemical quantitative detection of anthocyanins from natural products by using dual responsive and dummy molecularly imprinted polymers

作者全名："Jiang, Zhuang-Fei; Li, Qin; Li, Qing-Yao; Xu, Hui-Xian; He, Jia-Yuan; Wang, Chong-Zhi; Zhou, Lian-Di; Zhang, Qi-Hui; Luo, Ling; Yuan, Chun-Su"

作者地址："[Jiang, Zhuang-Fei; Li, Qin; Li, Qing-Yao; Xu, Hui-Xian; He, Jia-Yuan; Zhang, Qi-Hui] Chongqing Univ, Sch Chem & Chem Engn, Chongqing 400044, Peoples R China; [Zhou, Lian-Di] Chongqing Med Univ, Basic Med Coll, Chongqing 400016, Peoples R China; [Zhang, Qi-Hui; Luo, Ling] Chongqing Univ, Chongqing Canc Inst, Canc Hosp, Chongqing 400030, Peoples R China; [Wang, Chong-Zhi; Yuan, Chun-Su] Univ Chicago, Tang Ctr Herbal Med Res, Chicago, IL 60637 USA; [Wang, Chong-Zhi; Yuan, Chun-Su] Univ Chicago, Dept Anesthesia & Crit Care, Chicago, IL 60637 USA"

通信作者："Zhang, QH (通讯作者)，Chongqing Univ, Sch Chem & Chem Engn, Chongqing 400044, Peoples R China.; Zhou, LD (通讯作者)，Chongqing Med Univ, Basic Med Coll, Chongqing 400016, Peoples R China.; Zhang, QH; Luo, L (通讯作者)，Chongqing Univ, Chongqing Canc Inst, Canc Hosp, Chongqing 400030, Peoples R China."

来源：MICROCHEMICAL JOURNAL

ESI学科分类：CHEMISTRY

WOS号：WOS:000803554300006

JCR分区：Q1

影响因子：4.8

年份：2022

卷号：179

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Magnetic molecularly imprinted polymers; Dummy template; pH-responsive; Electrochemical detection

摘要："In this work, a new adsorbent was synthesized using dummy-template molecular imprinting technology, magnetic separation technology and pH-responsive technology, which was used to quickly enrich anthocyanins in fruit and detect with electrochemical methods. On the surface of magnetic particles, the molecularly-imprinted materials were synthesized by using quercetin as the dummy-template, 4-vinyl phenylboronic acid and methacrylic acid as the functional monomers. The microstructure was characterized by scanning electron microscopy, transmission electron microscope, Fourier transform infrared spectroscopy, N2 adsorption-desorption, thermal gravimetric analysis, vibrating sample magnetometer and X-ray photoelectron spectroscopy. Compared with structural analogue, dummy-template magnetic and pH-responsive molecularly imprinted polymers (DMMIPs) had shorter kinetic equilibrium time, higher selectivity and better adsorption capacity toward anthocyanins. The binding capacity and imprinting factor of the dummy molecularly imprinted polymer could reach 59.22 mg/g and 1.56, respectively. The anthocyanins' content of blueberry and grape peel crude extracts were consistent with the reference reports."

基金机构："National Natural Science Foundation of China [81973451]; Fundamental and Frontier Research Fund of Chongqing [cstc2018jcyjAX0661, cstc2019jsyj-yzysbAX0020]; Science and Technology Research Program of Chongqing Municipal Education Commission [KJZD-K201800103]; Fundamental Research Funds for the Central Univer-sities [2019CDYGYB027]; Graduate Research and Innovation Foundation of Chongqing [CYS18033]; Venture & Innovation Support Program for Chongqing Overseas Returnees; Tang Foundations"

基金资助正文："This work was financially supported by National Natural Science Foundation of China (No.81973451) , Fundamental and Frontier Research Fund of Chongqing (No. cstc2018jcyjAX0661, No. cstc2019jsyj-yzysbAX0020) , the Science and Technology Research Program of Chongqing Municipal Education Commission (No. KJZD-K201800103) , Fundamental Research Funds for the Central Universities (No. 2019CDYGYB027) , Graduate Research and Innovation Foundation of Chongqing (No. CYS18033) , Venture & Innovation Support Program for Chongqing Overseas Returnees, and Tang Foundations."