Reference values of impulse oscillometry (IOS) for healthy Chinese children aged 4-17 years

作者全名："Wu, Jinhong; Zhang, Hao; Shi, Yongsheng; Wang, Jinrong; Han, Yuling; Zhang, Qiaoling; Wang, Ning; Liu, Sha; Zhang, Yuehua; Zi, Huifen; Wang, Fei; Liu, Aihong; Song, Yuxin; Jia, ChunMei; Feng, Yong; Liu, Quanhua; Wan, Liya; Ji, Minghong; Long, Zhen; Huang, Jianfeng; Liu, Li; Sun, Yun; Tang, Suping; Dong, Xiaoyan; Zhou, Xiaojian; Jiang, Wenhui; Shen, Li; Jiang, Haohua"

作者地址："[Wu, Jinhong] Shanghai Jiao Tong Univ, Sch Med, Shanghai Childrens Med Ctr, Dept Resp Med, Shanghai 200127, Peoples R China; [Zhang, Hao] Shanghai Jiao Tong Univ, Sch Med, Shanghai Childrens Med Ctr, Dept Internal Med, Shanghai 200127, Peoples R China; [Shi, Yongsheng] Matern & Child Care Hosp Gansu Prov, Dept Pediat Resp, Lanzhou 730050, Gansu, Peoples R China; [Wang, Jinrong] Shandong First Med Univ, Affiliated Prov Hosp, Dept Pediat Resp, Jinan 250021, Peoples R China; [Han, Yuling] Shandong Univ, Qilu Childrens Hosp, Dept Resp, Jinan 250022, Peoples R China; [Zhang, Qiaoling] Maternal & Child Hlth Hosp Inner Mongolia Autonom, Dept Pediat Resp, Hohhot 010020, Peoples R China; [Wang, Ning] Xian Childrens Hosp, Asthma Ctr, Xian 710003, Peoples R China; [Liu, Sha] Chongqing Med Univ, Childrens Hosp, Dept Resp Med, Chongqing 400014, Peoples R China; [Zhang, Yuehua] Cent South Univ, Affiliated Haikou Hosp, Xiangya Sch Med, Pediat Infect Dis Ward, Haikou 570208, Hainan, Peoples R China; [Zi, Huifen] Baotou Cent Hosp, Dept Pediat, Baotou 014040, Peoples R China; [Wang, Fei] Guiyang Childrens Hosp, Guiyang Maternal & Child Hlth Hosp, Dept Pediat Resp, Guiyang 550003, Peoples R China; [Liu, Aihong] Childrens Hosp Shanxi, Dept Resp Med, Taiyuan 030013, Peoples R China; [Song, Yuxin] Harbin Childrens Hosp, Dept Allergy, Harbin 150010, Peoples R China; [Jia, ChunMei] Baotou Childrens Hosp, Hosp Baotou 4, Dept Pediat Resp, Baotou 014030, Peoples R China; [Feng, Yong] China Med Univ, Shengjing Hosp, Dept Pediat, Shenyang 110004, Peoples R China; [Liu, Quanhua] Shanghai Jiao Tong Univ, Sch Med, Xinhua Hosp, Dept Pulmonol, Shanghai 200092, Peoples R China; [Wan, Liya] Tianjin Childrens Hosp, Resp Dept, Tianjin 300074, Peoples R China; [Ji, Minghong] USTC, Anhui Prov Hosp, Affiliated Hosp 1, Dept Pediat, Hefei 230001, Peoples R China; [Long, Zhen] Huazhong Univ Sci & Technol, Maternal & Child Hlth Hosp Hubei Prov, Tongji Med Coll, Dept Pediat Resp Med, Wuhan 430070, Peoples R China; [Huang, Jianfeng] Fudan Univ, Childrens Hosp, Dept Pulmonol, Shanghai 201102, Peoples R China; [Liu, Li] First Hosp Jilin Univ, Dept Pediat Resp, Changchun 130021, Peoples R China; [Sun, Yun] Yinchuan Women & Children Healthcare Hosp, Gen Pediat, Yinchuan 750001, Ningxia, Peoples R China; [Tang, Suping] Fujian Med Univ, Fuzhou Childrens Hosp, Dept Asthma & Tracheitis, Fuzhou 350000, Peoples R China; [Dong, Xiaoyan] Shanghai Jiao Tong Univ, Shanghai Childrens Hosp, Dept Pulmonol, Shanghai 200040, Peoples R China; [Zhou, Xiaojian] Shanghai Jiao Tong Univ, Shanghai Peoples Hosp 1, Dept Pediat, Shanghai 200080, Peoples R China; [Jiang, Wenhui] Guangzhou Women & Childrens Med Ctr, Dept Resp, Guangzhou 510623, Peoples R China; [Shen, Li; Jiang, Haohua] Shanghai Jiao Tong Univ, Shanghai Chest Hosp, Dept Resp, Shanghai 200025, Peoples R China"

通信作者："Zhang, H (通讯作者)，Shanghai Jiao Tong Univ, Sch Med, Shanghai Childrens Med Ctr, Dept Internal Med, Shanghai 200127, Peoples R China."

来源：RESPIRATORY RESEARCH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000824699400001

JCR分区：Q1

影响因子：5.8

年份：2022

卷号：23

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Impulse oscillometry; Pulmonary function test; Normal predicted value; Child

摘要："Objective To establish the predicted value of pulmonary function determined by impulse oscillometry (IOS) in children (4-17 years old) in China. Methods A total of 6270 healthy children aged 4-17 years in China were included. The Master Screen IOS pulmonary function device (Jaeger Co, Germany) was used to detect the respiratory impedance (Zrs), resonant frequency (Fres), respiratory system resistance (Rrs) and respiratory system reactance (Xrs) at various oscillation frequencies, and the indices above were analysed. Stepwise multivariate regression was used to establish the regression equation of related parameters of IOS in different sexes, ages, height, and weight. Results The differences in the main IOS parameters between different age stages were statistically significant regardless of sex (P < 0.05). The stepwise multivariate regression analysis showed that IOS parameters were related to height, age, and weight, and most IOS parameters were most closely related to height (the absolute value of the regression coefficient was the largest). With increasing age and height, the values of Z(5), R-5, R-20, R-5-R-20, and Fres decreased, while the value of X-5 increased. Through height, age, and weight, we obtained the normal predicted values equation of children's IOS parameters. Compared with the other reference equations, our reference equation is more suitable for Chinese children. Conclusions The study revealed the reference values of IOS parameters in healthy Chinese children. In the evaluation of results for lung function measurements, this predicted value equation is more consistent with the characteristics of Chinese children than other reference equations. Clinical Trial: ChiCTR: 1800019029."

基金机构："Shanghai Medical Guidance, Science and Technology Support project of Traditional Chinese Medicine [19401931800]; Innovation Fund for Combination of Chinese Traditional and Western Medicine, Shanghai Jiao Tong University School of Medicine [18zxy007]; Shanghai Municipal Natural Science Foundation [21ZR1440800]"

基金资助正文："Shanghai Medical Guidance, Science and Technology Support project of Traditional Chinese Medicine and Western Medicine (19401931800); Innovation Fund for Combination of Chinese Traditional and Western Medicine, Shanghai Jiao Tong University School of Medicine(18zxy007); Shanghai Municipal Natural Science Foundation(21ZR1440800)."