Prevalence and risk of atrial fibrillation in China: A national cross-sectional epidemiological study

作者全名："Shi, Shaobo; Tang, Yanhong; Zhao, Qingyan; Yan, Hong; Yu, Bin; Zheng, Qiangsun; Li, Yigang; Zheng, Liangrong; Yuan, Yiqiang; Zhong, Jingquan; Xu, Jian; Wu, Yanqing; Xu, Jing; Chen, Lin; Li, Shufeng; Jiang, Jian; Wang, Jingfeng; Fan, Jie; Chen, Minglong; Tang, Baopeng; Li, Wei; Wu, Qiang; Shi, Bei; Zhou, Shenghua; Zhao, Xingsheng; Yin, Yuehui; Zhang, Zheng; Zhong, Guoqiang; Han, Xuebin; Liu, Fan; Wu, Ming; Gao, Lianjun; Yang, Bo; Huang, He; Huang, Congxin; behalf China Atrial Fibrillation Ctr Project Team"

作者地址："[Shi, Shaobo; Tang, Yanhong; Zhao, Qingyan; Yang, Bo; Huang, He; Huang, Congxin] Wuhan Univ, Dept Cardiol, Renmin Hosp, 238 Jiefang Rd, Wuhan 430060, Hubei, Peoples R China; [Shi, Shaobo; Tang, Yanhong; Zhao, Qingyan; Yang, Bo; Huang, He; Huang, Congxin] Wuhan Univ, Cardiovasc Res Inst, Wuhan 430060, Peoples R China; [Shi, Shaobo; Tang, Yanhong; Zhao, Qingyan; Yang, Bo; Huang, He; Huang, Congxin] Wuhan Univ, Hubei Key Lab Cardiol, Wuhan 430060, Peoples R China; [Yan, Hong; Yu, Bin] Wuhan Univ, Sch Publ Hlth, Wuhan 430071, Peoples R China; [Zheng, Qiangsun] Xi An Jiao Tong Univ, Affiliated Hosp 2, Xian 710004, Peoples R China; [Li, Yigang] Shanghai Jiao Tong Univ, Xinhua Hosp, Sch Med, Shanghai 200092, Peoples R China; [Zheng, Liangrong] Zhejiang Univ, Affiliated Hosp 1, Sch Med, Hangzhou 310003, Peoples R China; [Yuan, Yiqiang] Henan Prov Chest Hosp, Zhengzhou 450008, Peoples R China; [Zhong, Jingquan] Shandong Univ, Qilu Hosp, Jinan 250063, Peoples R China; [Xu, Jian] Anhui Prov Hosp, Hefei 230001, Peoples R China; [Wu, Yanqing] Nanchang Univ, Affiliated Hosp 2, Nanchang 330006, Peoples R China; [Xu, Jing] Tianjin Chest Hosp, Tianjin 300222, Peoples R China; [Chen, Lin] Fujian Prov Hosp, Fuzhou 350013, Peoples R China; [Li, Shufeng] Harbin Med Univ, Affiliated Hosp 2, Harbin 150086, Peoples R China; [Jiang, Jian] Sichuan Univ, West China Hosp, Chengdu 610044, Peoples R China; [Wang, Jingfeng] Sun Yat sen Mem Hosp, Guangzhou 510120, Peoples R China; [Fan, Jie] First Peoples Hosp Yunnan Prov, Kunming 650034, Peoples R China; [Chen, Minglong] Jiangsu Prov Hosp, Nanjing 210029, Peoples R China; [Tang, Baopeng] Xinjiang Med Univ, Affiliated Hosp 1, Urumqi 830011, Peoples R China; [Li, Wei] Guizhou Med Univ, Affiliated Hosp, Guiyang 550004, Guizhou, Peoples R China; [Wu, Qiang] Guizhou Prov Peoples Hosp, Guiyang 550002, Guizhou, Peoples R China; [Shi, Bei] Zunyi Med Univ, Affiliated Hosp, Zunyi 563099, Peoples R China; [Zhou, Shenghua] Cent South Univ, Xiangya Hosp 2, Changsha 430062, Peoples R China; [Zhao, Xingsheng] Inner Mongolia Autonomous Reg Peoples Hosp, Hohhot 010020, Peoples R China; [Yin, Yuehui] Chongqing Med Univ, Affiliated Hosp 1, Chongqing 400010, Peoples R China; [Zhang, Zheng] First Hosp Lanzhou Univ, Lanzhou 730013, Peoples R China; [Zhong, Guoqiang] Guangxi Med Univ, Affiliated Hosp 1, Nanning 530021, Peoples R China; [Han, Xuebin] Shanxi Cardiovasc Hosp, Taiyuan 030024, Peoples R China; [Liu, Fan] Second Hosp Hebei Med Univ, Shijiazhuang 050004, Peoples R China; [Wu, Ming] Hainan Gen Hosp, Haikou 570311, Peoples R China; [Gao, Lianjun] Dalian Med Univ, Affiliated Hosp 1, Dalian 116051, Peoples R China"

通信作者："Huang, H; Huang, CX (通讯作者)，Wuhan Univ, Dept Cardiol, Renmin Hosp, 238 Jiefang Rd, Wuhan 430060, Hubei, Peoples R China."

来源：LANCET REGIONAL HEALTH-WESTERN PACIFIC

ESI学科分类：　

WOS号：WOS:000829486900002

JCR分区：Q1

影响因子：7.1

年份：2022

卷号：23

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：Atrial fibrillation; Prevalence; Factor; Adult; China

摘要："Background Atrial fibrillation (AF) is the most common persistent cardiac arrhythmia. This study aimed to estimate its prevalence and explore associated factors in adults aged 18 years or older in China. Methods Study data were derived from a national sample from July 2020 to September 2021. Participants were recruited using a multistage stratified sampling method from twenty-two provinces, autonomous regions, and municipalities in China. AF was determined based on a history of diagnosed AF or electrocardiogram results. Findings A total of 114,039 respondents were included in the final analysis with a mean age of 55 years (standard deviation 17), 52.1% of whom were women. The crude prevalence of AF was 2.3% (95% confidence interval [CI] 1.7-2.8) and increased with age. The age-standardized AF prevalence was 1.6% (95% CI 1.6-1.7%) overall, and 1.7% (1.6-1.8%), 1.4% (1.3-1.5%), 1.6% (95% CI 1.5-1.7%), and 1.7% (1.6-1.9%) in men, women, urban areas, and rural areas, respectively. The prevalence was higher in the central regions (2.5%, 2.3-2.7%) than in the western regions (1.5%, 1.0-2.0%) and eastern regions (1.1%, 1.0-1.2%) in the overall population, either in the gender or residency subgroups. The associated factors for AF included age (per 10 years; odds ratio 1.41 [95% CI 1.38-1.46]; p < 0.001), men (1.34 [1.24-1.45]; p < 0.001), hypertension (1.22 [1.12-1.33]; p < 0.001), coronary heart disease (1.44 [1.28-1.62]; p < 0.001), chronic heart failure (3.70 [3.22-4.26]; p < 0.001), valvular heart disease (2.13 [1.72-2.63]; p < 0.001), and transient ischaemic attack/stroke (1.22 [1.04-1.43]; p = 0.013). Interpretation The prevalence of AF was 1.6% in the Chinese adult population and increased with age, with significant geographic variation. Older age, male sex, and cardiovascular disease were potent factors associated with AF. It is crucial to increase the awareness of AF and disseminate standardized treatment in clinical settings to reduce the disease burden. Copyright (c) 2022 Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/)"

基金机构：Second Affiliated Hospital of Xian Jiaotong University; Xinhua Hospital; First Affiliated Hospital; Zhejiang University School of Medicine; Henan Provincial Chest Hospital; Qilu Hospital of Shandong University; Anhui Provincial Hospital; Second Affiliated Hospital of Nanchang University; Tianjin Chest Hospital; Fujian Provincial Hospital; Second Affiliated Hospital of Harbin Medical University; West China Hospital of Sichuan University; Sun Yatsen Memorial Hospital; Second People's Hospital of Yunnan Province; Jiangsu Province Hospital; First Affiliated Hospital of Xinjiang Medical University; Affiliated Hospital of Guizhou Medical University; Guizhou Provincial People's Hospital; Affiliated Hospital of Zunyi Medical University; Second Xiangya Hospital of Central South University; Inner Mongolia Autonomous Region People 's Hospital; Second Affiliated Hospital of Chongqing Medical University; First Hospital of Lanzhou University; First Affiliated Hospital of Guangxi Medical University; Shanxi Cardiovascular Hospital; Second Hospital of Hebei Medical University; Hainan General Hospital; First Affiliated Hospital of Dalian Medical University

基金资助正文："We thank Junbo Ge, Yong Huo and other consultants for their instructions and contributions through the whole process of study; Shinall Technology for providing database network and screening equipment. We acknowledge the support provided by all partnership, including The Second Affiliated Hospital of Xian Jiaotong University; Xinhua Hospital Affiliated To Shanghai Jiao Tong University School of Medicine; The First Affiliated Hospital; Zhejiang University School of Medicine; Henan Provincial Chest Hospital; Qilu Hospital of Shandong University; Anhui Provincial Hospital; The Second Affiliated Hospital of Nanchang University; Tianjin Chest Hospital; Fujian Provincial Hospital; The Second Affiliated Hospital of Harbin Medical University; West China Hospital of Sichuan University; Sun Yatsen Memorial Hospital; The Second People's Hospital of Yunnan Province; Jiangsu Province Hospital; The First Affiliated Hospital of Xinjiang Medical University; The Affiliated Hospital of Guizhou Medical University; Guizhou Provincial People's Hospital; Affiliated Hospital of Zunyi Medical University; The Second Xiangya Hospital of Central South University; Inner Mongolia Autonomous Region People 's Hospital; The Second Affiliated Hospital of Chongqing Medical University, The First Hospital of Lanzhou University; The First Affiliated Hospital of Guangxi Medical University; Shanxi Cardiovascular Hospital; The Second Hospital of Hebei Medical University; Hainan General Hospital; The First Affiliated Hospital of Dalian Medical University. We thank all provincial and regional officers and research staff in China for their collection of data."