Size-Tunable Yolk-Shell Gold-Silver Nanostructures for Photothermal Treatment of Multidrug-Resistant Bacteria

作者全名："Zhang, Haifeng; Tan, Juan; Yang, Xiaoqin; Ma, Yanyun; Zou, Hongyan; Wang, Yi; Zhang, Pu; Zheng, Yiqun"

作者地址："[Zhang, Haifeng; Zheng, Yiqun] Jining Univ, Sch Chem Chem Engn & Mat, Qufu 273155, Shandong, Peoples R China; [Tan, Juan; Wang, Yi] Chongqing Normal Univ, Coll Chem, Chongqing Key Lab Green Synth & Applicat, Chongqing 401331, Peoples R China; [Yang, Xiaoqin; Zhang, Pu] Chongqing Med Univ, Coll Pharm, Chongqing Res Ctr Pharmaceut Engn, Chongqing 400016, Peoples R China; [Ma, Yanyun] Soochow Univ, Inst Funct Nano & Soft Mat FUNSOM, Jiangsu Key Lab Carbon Based Funct Mat & Devices, Suzhou 215123, Jiangsu, Peoples R China; [Zou, Hongyan] Southwest Univ, Coll Pharmaceut Sci, Key Lab Luminescence Anal & Mol Sensing, Minist Educ, Chongqing 400715, Peoples R China"

通信作者："Zheng, YQ (通讯作者)，Jining Univ, Sch Chem Chem Engn & Mat, Qufu 273155, Shandong, Peoples R China.; Wang, Y (通讯作者)，Chongqing Normal Univ, Coll Chem, Chongqing Key Lab Green Synth & Applicat, Chongqing 401331, Peoples R China.; Zhang, P (通讯作者)，Chongqing Med Univ, Coll Pharm, Chongqing Res Ctr Pharmaceut Engn, Chongqing 400016, Peoples R China."

来源：ACS APPLIED NANO MATERIALS

ESI学科分类：　

WOS号：WOS:000835945100001

JCR分区：Q2

影响因子：5.9

年份：2022

卷号：5

期号：8

开始页：10818

结束页：10828

文献类型：Article

关键词：noble metal; nanocrystals; photothermal; nanoframe; antibacterial

摘要："Framelike nanostructures consisting of interconnected, ultrathin ridges have attracted wide attention due to their high atomic utilization efficiency among typical hollow architectures but are yet to be comprehensively studied for photothermal applications. Herein, we report a facile synthesis of AuAg yolk- shell cubic nanoframes (YSCNFs) with tunable edge lengths, followed by the exploration of their photothermal conversion and in vitro bacteria-killing performance, together with our endeavors to understand the mechanism fundamentally. By adopting the rationally screened capping agent docosyltrimethylammonium chloride (DCTAC) throughout the stepwise synthesis, sharp cubic edges could be generated and largely reserved, leaving the 5 nm cubic nanoframes well standing. The increase in the cubic edge length leads to the red shift of the major LSPR absorption peak toward the NIR region, and abundant hot-spots appear at the frame corner and core surface according to finite-difference time-domain (FDTD) simulation. The photothermal conversion efficiency of YSCNFs can reach as high as 65.6% when a very low power density of 0.27 W cm(-2) is used, which displays a powerful ability in combating multidrug-resistant bacteria. The present study offers a systematic investigation of bimetallic yolk-shell nanoframes including size/morphology control, photothermal properties, mechanism studies, and antibacterial applications, which could be of great value for the rational design of high-efficiency photothermal nanomaterials for services to biomedicine."

基金机构：Natural Science Foundation of China [21701100]; Young Innovative Talents Introduction and Cultivation Program for Colleges and Universities of Shandong Province - Department of Education of Shandong Province [2020BSZX01]; Distinguished Hundred Talent Program of Jining University [2020ZYRC05]; Scientific and Technological Innovation Key Project for Construction of Double City Economic Circle in Chengdu-Chongqing Region [KJCXZD2020024]; Chongqing Innovation Research Group Project [CXQT21015]; Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices (Soochow University) [KS2022]; Collaborative Innovation Center of Suzhou Nano Science and Technology; Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD); 111 Project; Joint International Research Laboratory of Carbon-Based Functional Materials and Devices

基金资助正文："This work was financially supported by the Natural Science Foundation of China (Grant No. 21701100) , Young Innovative Talents Introduction and Cultivation Program for Colleges and Universities of Shandong Province (Granted by the Department of Education of Shandong Province, Subtitle: Innovative Research Team on Optoelectronic Functional Materials) , Doctoral Startup Research Funding of Jining University (Grant No. 2020BSZX01) , Distinguished Hundred Talent Program (Grant No. 2020ZYRC05) of Jining University, Scientific and Technological Innovation Key Project for Construction of Double City Economic Circle in Chengdu-Chongqing Region (Grant No. KJCXZD2020024) , and Chongqing Innovation Research Group Project (Grant No. CXQT21015) . This work is also supported by the open project (Grant No. KS2022) of Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices (Soochow University), Collaborative Innovation Center of Suzhou Nano Science and Technology, the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), the 111 Project, and the Joint International Research Laboratory of Carbon-Based Functional Materials and Devices."