Patient-Controlled Intravenous Analgesia With Tramadol and Lornoxicam After Thoracotomy: A Comparison With Patient-Controlled Epidural Analgesia

作者全名："Jin, Juying; Min, Su; Chen, Qibin; Zhang, Dong"

作者地址："[Jin, Juying; Min, Su; Chen, Qibin; Zhang, Dong] Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, Chongqing, Peoples R China; [Min, Su] Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, 1 Youyi Rd, Chongqing 400016, Peoples R China"

通信作者："Min, S (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：INTERNATIONAL SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000864077100005

JCR分区：Q4

影响因子：0.1

年份：2022

卷号：106

期号：2

开始页：75

结束页：81

文献类型：Article

关键词：Analgesia; Patient controlled; Pain; Postoperative; Thoracotomy; Tramadol; Lornoxicam

摘要："Objective: To determine efficacy and safety of patient-controlled intravenous analgesia (PCIA) with tramadol and lornoxicam for postoperative analgesia, and its effects on surgical outcomes in patients after thoracotomy. Summary of background data: Adequate pain relief after thoracic surgery is of particular importance, not only for keeping patients comfortable but also for reducing the incidence of postoperative complications. PCIA with tramadol and lornoxicam could be an acceptable alternative to patient-controlled epidural analgesia (PCEA) for pain management after thoracotomy. Methods: The records of patients who underwent thoracotomy for lung resection between January 2014 and December 2014 at our institution were reviewed. The patients were divided into 2 groups according to postoperative pain treatment modalities. Patients of PCEA group (n = 63) received PCEA with 0.2% ropivacaine plus 0.5 lg/mL sufentanil, while patients in PCIA group (n = 48) received PCIA with 5 mg/mL tramadol and 0.4 mg/mL lornoxicam. Data were collected for quality of pain control, incidences of analgesia-related side effects and pulmonary complications, lengths of thoracic intensive care unit stay and postoperative hospital stay, and in-hospital mortality. Results: Pain at rest was controlled well in both groups during a 4-day postoperative period. Patients in PCIA group reported significantly higher pain scores on coughing and during mobilization in the first 2 postoperative days. The incidences of side effects and pulmonary complications, in-hospital mortality, and other outcomes were similar between groups. Conclusions: PCIA with tramadol and lornoxicam can be considered as a safe and effective alternative with respect to pain control and postoperative outcomes after thoracotomy."

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