Effect of the anastomosis between the posterior inferior cerebellar artery and the superior cerebellar artery on outcomes of acute basilar artery occlusion after endovascular treatment

作者全名："Huang, Jiacheng; Kong, Weilin; Yang, Jie; Wang, Maolin; Huang, Xianjun; Wang, Yan; Luo, Jun; Wu, Youlin; Zeng, Guoyong; Wan, Yue; Song, Jiaxing; Li, Linyu; Hu, Jinrong; Liu, Shuai; Luo, Weidong; Tian, Yan; Sang, Hongfei; Qiu, Zhongming; Li, Fengli; Schonewille, Wouter; Liu, Chang; Zi, Wenjie"

作者地址："[Huang, Jiacheng; Liu, Chang; Zi, Wenjie] Chongqing Med Univ, Dept Neurol, Affiliated Hosp 2, Chongqing, Peoples R China; [Huang, Jiacheng; Kong, Weilin; Yang, Jie; Song, Jiaxing; Li, Linyu; Hu, Jinrong; Liu, Shuai; Luo, Weidong; Tian, Yan; Sang, Hongfei; Qiu, Zhongming; Li, Fengli; Zi, Wenjie] Army Med Univ, Dept Neurol, Xinqiao Hosp, Chongqing, Peoples R China; [Wang, Maolin] Army Med Univ, Cent Lab, Xinqiao Hosp, Chongqing, Peoples R China; [Huang, Xianjun] Wannan Med Coll, Dept Neurol, Affiliated Hosp 1, Wuhu, Peoples R China; [Wang, Yan] Chengdu Fifth Peoples Hosp, Dept Neurol, Chengdu, Peoples R China; [Luo, Jun] 404 Hosp, Dept Neurol, Mianyang, Sichuan, Peoples R China; [Wu, Youlin] Peoples Hosp Chongzhou, Dept Neurol, Chongzhou, Peoples R China; [Zeng, Guoyong] Ganzhou Peoples Hosp, Dept Neurol, Ganzhou, Jiangxi, Peoples R China; [Wan, Yue] Yangluo Dist Hubei Zhongshan Hosp, Dept Neurol, Wuhan, Hubei, Peoples R China; [Schonewille, Wouter] Sint Antonius Ziekenhuis, Dept Neurol, Nieuwegein, Netherlands"

通信作者："Liu, C; Zi, WJ (通讯作者)，Chongqing Med Univ, Dept Neurol, Affiliated Hosp 2, Chongqing, Peoples R China.; Zi, WJ (通讯作者)，Army Med Univ, Dept Neurol, Xinqiao Hosp, Chongqing, Peoples R China."

来源：JOURNAL OF NEUROINTERVENTIONAL SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000864322400001

JCR分区：Q1

影响因子：4.8

年份：2022

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Stroke; Thrombectomy

摘要："Background The effects of secondary collateral compensation on outcomes remain unclear in patients with acute basilar artery occlusion (BAO) after endovascular treatment (EVT). This study aimed to evaluate the benefits of the anastomosis between the posterior inferior cerebellar artery (PICA) and the superior cerebellar artery (SCA) in BAO after EVT. Methods This cohort study was conducted using data from the Endovascular Treatment for Acute Basilar Artery Occlusion Study Registry. Patients with acute BAO and treated with EVT were included. The primary outcome was a modified Rankin Scale score of 0-2 at 90 days. Safety outcomes included symptomatic intracerebral hemorrhage (SICH) and 90-day mortality. Results Of the 646 patients included in the study, 196 (30.3%) patients had a PICA-SCA anastomosis. The PICA-SCA anastomosis was significantly associated with independent functional outcome at 90 days (67/196 (34.2%) vs 109/450 (24.2%), adjusted OR (aOR) 1.80 (95% CI 1.13 to 2.86), p=0.01) and was significantly associated with a decreased rate of SICH (40/442 (9.0%) vs 5/193 (2.6%), aOR 0.29 (95% CI 0.11 to 0.76), p=0.01). No significant difference was found between PICA-SCA anastomosis and 90-day mortality (219/450 (48.7%) vs 80/196 (40.8%), aOR 0.72 (95% CI 0.48 to 1.08), p=0.11). Subgroup analysis showed that the association between independent functional outcome and PICA-SCA anastomosis was strongest in patients with middle BAO (27/77 (35.1%) vs 22/118 (18.6%), aOR 2.64 (95% CI 1.13 to 6.15), p=0.03). Conclusions The PICA-SCA anastomosis is significantly associated with better functional outcomes in patients with acute BAO after EVT, especially in those with middle BAO."

基金机构：National Natural Science Foundation of China [82071323]; Chongqing Natural Science Foundation [cstc2020jcyj-msxmX0926]

基金资助正文："This work was supported by the National Natural Science Foundation of China (No 82071323), Chongqing Natural Science Foundation (cstc2020jcyj-msxmX0926)."