Development and Validation of a Novel Nomogram to Predict Hypoalbuminemia among Patients with Stroke in the Neurocritical Care Unit

作者全名："Li, Junzhuo; Liu, Guangwei; Li, Feng; Yang, Wen; Zhang, Ruixin; Yang, Jiajia"

作者地址："[Li, Junzhuo; Liu, Guangwei; Li, Feng; Yang, Wen; Zhang, Ruixin; Yang, Jiajia] Chongqing Med Univ, Affiliated Hosp 1, Chongqing, Peoples R China"

通信作者："Liu, GW (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept, Med Coll Rd, Chongqing 400016, Peoples R China."

来源：CLINICAL NURSING RESEARCH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000864429100001

JCR分区：Q2

影响因子：1.7

年份：2022

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：hypoalbuminemia; nomogram; stroke; risk factors

摘要："This study aimed to investigate hypoalbuminemia-related factors in patients with stroke in the neurocritical care unit (NCU) and to establish a nomogram model for hypoalbuminemia prediction. Data from 902 patients hospitalized for stroke in the NCU who had normal albumin levels on admission from March 2018 to December 2020 were analyzed. Logistic regression was used to identify the risk factors associated with hypoalbuminemia. A novel nomogram prediction model for hypoalbuminemia was constructed, and it was validated in an independent set (n = 233). The nomogram incorporated seven risk factors, including age, high comorbidity, mechanical ventilation, feeding routes, total protein, high-sensitivity C-reactive protein, and fibrinogen levels, and its area under the curve for predicting hypoalbuminemia in the developmental set and validation set were 0.856 and 0.870, respectively. The novel nomogram facilitates risk prediction of hypoalbuminemia among patients with stroke in the NCU, which might be useful for selecting treatment strategies and management."

基金机构：　

基金资助正文：