Risk factors and a simple scoring system for predicting bowel resection in infants with NEC

作者全名："Li, Ping; Wang, Bo; Tang, Xuefei; Guo, Chunbao; Zhang, Dianliang"

作者地址："[Li, Ping] Qingdao Univ, Affiliated Hosp, Dept Abdominal Ultrasound, 16 Jiangsu Rd, Qingdao 266003, Shandong, Peoples R China; [Wang, Bo] Qingdao Multicipal Hosp, West Hosp Dist, Dept Phys Diagnost, 2 Chaocheng Rd, Qingdao 266002, Shandong, Peoples R China; [Tang, Xuefei; Zhang, Dianliang] Qingdao Univ, Qingdao Municipal Hosp, Dept Gen Surg 1, 1 Jiaozhou Rd, Qingdao 266011, Shandong, Peoples R China; [Guo, Chunbao] Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat Surg, Chongqing, Peoples R China; [Guo, Chunbao] Chongqing Hlth Ctr Women & Children, Dept Pediat Surg, Chongqing, Peoples R China; [Guo, Chunbao; Zhang, Dianliang] Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat Surg, 120 Longshan Rd, Chongqing 400014, Peoples R China; [Guo, Chunbao; Zhang, Dianliang] Qingdao Univ, Qingdao Municipal Hosp, Dept Gen Surg 1, 1 Jiaozhou Rd, Qingdao 266011, Shandong, Peoples R China"

通信作者："Zhang, DL (通讯作者)，Qingdao Univ, Qingdao Municipal Hosp, Dept Gen Surg 1, 1 Jiaozhou Rd, Qingdao 266011, Shandong, Peoples R China.; Guo, CB (通讯作者)，Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat Surg, Chongqing, Peoples R China.; Guo, CB (通讯作者)，Chongqing Hlth Ctr Women & Children, Dept Pediat Surg, Chongqing, Peoples R China.; Guo, CB; Zhang, DL (通讯作者)，Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat Surg, 120 Longshan Rd, Chongqing 400014, Peoples R China.; Guo, CB; Zhang, DL (通讯作者)，Qingdao Univ, Qingdao Municipal Hosp, Dept Gen Surg 1, 1 Jiaozhou Rd, Qingdao 266011, Shandong, Peoples R China."

来源：CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000868494200007

JCR分区：Q2

影响因子：2.7

年份：2022

卷号：46

期号：9

开始页：　

结束页：　

文献类型：Article

关键词：Necrotizing enteroco-litis (NEC); Risk factors; Laparotomy; Bowel resection

摘要："Background and aims: We intended to investigate the predictors for bowel resection in infants with necrotizing enterocolitis (NEC). We further developed a scoring system for better predicting bowel resection.Methods: A total of 207 infants who underwent surgical management at Children's Hospital, Chongqing Medical University between April 2008 and December 2020 were identified for the fol-lowing investigation. Bowel resection was reviewed among the infants who underwent the pro-cedure. Potential parameters related to bowel resection were explored using a multiple logistic regression method, and then a scoring system was developed.Results: Among the 207 patients who underwent operative intervention that were reviewed, 109 infants underwent bowel resection. Multivariate logistic regression analysis showed that birth weight, hypotension, neutropenia, pneumoperitoneum, acidosis, and intestinal wall thickness were predictors related to the occurrence of bowel resection. A 6 -point scoring system was further developed based on the obtained total coefficient, and the infants could be divided into low-, moderate-and high-risk groups according to cut val-ues of 7 and 13.Conclusion: The results of this study demonstrated that severe NEC features and low birth weight were associated with bowel resection. The risk scoring system could accurately separate infants that were suspected to have bowel loss during surgery.(c) 2022 Published by Elsevier Masson SAS."

基金机构："National Natural Science Foundation of China [30973440, 30770950]; Key Project of the Chongqing Natural Science Foundation [CSTC, 2008BA0021, cstc2012jjA0155]; Chongqing Health Planning Commission of Research Fund [2016MSXM044]"

基金资助正文："This study was supported by grants from the National Natural Science Foundation of China (Nos: 30973440 and 30770950) in the design of the study; the Key Project of the Chongqing Natural Science Foundation (CSTC, 2008BA0021, cstc2012jjA0155) for collection, analysis, and interpretation of data; and the Chongqing Health Planning Commission of Research Fund (No: 2016MSXM044) in writing the manuscript."