The Effectiveness and Rotational Stability of Vertical Implantation of the Implantable Collamer Lens for the Treatment of Myopia

作者全名："Huang, Wanyao; Ji, Yan; Zheng, Shijie; Huang, Fanfan; Zhang, Tong; Cheng, Hong; Li, Zhouyu; Gao, Ning; Du, Miaomiao; Zuo, Hangjia; Wan, Wenjuan; Hu, Ke"

作者地址："[Wan, Wenjuan; Hu, Ke] Chongqing Med Univ, Affiliated Hosp 1, Chongqing Key Lab Ophthalmol, Chongqing 400016, Peoples R China; [Wan, Wenjuan; Hu, Ke] Chongqing Med Univ, Chongqing Eye Inst, Chongqing 400016, Peoples R China"

通信作者："Wan, WJ; Hu, K (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Chongqing Key Lab Ophthalmol, Chongqing 400016, Peoples R China.; Wan, WJ; Hu, K (通讯作者)，Chongqing Med Univ, Chongqing Eye Inst, Chongqing 400016, Peoples R China."

来源：JOURNAL OF REFRACTIVE SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000874411800001

JCR分区：Q1

影响因子：2.4

年份：2022

卷号：　

期号：　

开始页：641

结束页：647

文献类型：Article; Early Access

关键词：　

摘要："PURPOSE: To explore the effectiveness and rotational stabil -ity of vertical implantation of the Implantable Collamer Lens (ICL) (STAAR Surgical) to treat myopia. .METHODS: This was a prospective, randomized, controlled study, including 78 eyes from 46 patients with myopia who un- derwent ICL implantation. The patients were randomly divided into vertical and horizontal implantation groups. At 1 day, 1 week, 1 month, and 3 months after surgery, rotational stability was evaluated using the postoperative axis deviation from the intended axis by the digital anterior segment photograph. The vault, crystalline lens rise, anterior chamber depth, manifest refraction spherical equivalent, intraocular pressure, and vi- sual acuity values were obtained before and after surgery.RESULTS: A 3-month follow-up period showed significant dif- ferences between the efficacy indexes in the horizontal (1.11 +/- 0.02) and vertical (1.13 +/- 0.02) groups (P = .455). No significant difference was observed in the postoperative manifest refrac- tion spherical equivalent between the horizontal (-0.27 +/- 0.18 diopters) and vertical (0.01 +/- 0.08 diopters) groups (P = .151). Also, no statistically significant difference was observed in the corneal endothelial cells and intraocular pressure between groups (P = .555, P = .464). The rotation angle of the horizontal group was greater at 1 week, 1 month, and 3 months (3.14 degrees +/- 2.13 degrees, 2.97 degrees +/- 2.01 degrees, 3.27 degrees +/- 2.12 degrees, respectively) compared to that of the vertical group (1.30 degrees +/- 1.29 degrees, 1.85 degrees +/- 1.60 degrees, 1.74 degrees +/- 1.33 degrees, respectively) (P < .001 for all). From 1 week to 3 months, the changing angle of horizontal (0.31 degrees +/- 1.86 degrees) and vertical (0.49 degrees +/- 1.33 degrees) ICL rotation displayed a positive correlation with the changing vault of horizontal (48.41 +/- 86.02 mm) and vertical (39.64 +/- 78.43 mm) ICL rotation (r = 0.242, 0.335, P = .033, .037). CONCLUSIONS: The study supports great efficacy and safety in both vertical and horizontal implantation, with the vertical implantation group displaying better stability.[J RefractSurg. 2022;38(10):641-647.]"

基金机构：National Natural Science Foundation of China; Project Foundation of Chongqing Science and Technology Commission of China; Chongqing Education Commission Project Fund of China; Chongqing Medical University; [81870650]; [82000883]; [81900885]; [81970832]; [cstc2020jcyj-msxmX0829]; [KJQN202000445]; [YJSZHYX202118]

基金资助正文："Supported by the National Natural Science Foundation of China (Grant Nos. 81870650, 82000883, 81900885, and 81970832) , the Project Foundation of Chongqing Science and Technology Commission of China (Grant No. cstc2020jcyj-msxmX0829) , Chongqing Education Commission Project Fund of China (Grant No. KJQN202000445) , and Chongqing Medical University (Grant No. YJSZHYX202118) ."