Long-term follow-up results of testicular torsion in children

作者全名："Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Hong, Yi-Fan; Zhao, Tian-Xin; Wen, Sheng; Jiang, Li; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De"

作者地址："[Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Hong, Yi-Fan; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] Chongqing Med Univ, Childrens Hosp, Dept Urol, Chongqing 400014, Peoples R China; [Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] Chongqing Key Lab Children Urogenital Dev & Tissue, Chongqing 400014, Peoples R China; [Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] Natl Clin Res Ctr Child Hlth & Disorders, Chongqing 400014, Peoples R China; [Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Hong, Yi-Fan; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] China Int Sci & Technol Cooperat Base Child Dev &, Chongqing 400014, Peoples R China; [Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Hong, Yi-Fan; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] Chongqing Key Lab Pediat Chongqing, Chongqing 400014, Peoples R China; [Yu, Cheng-Jun; Zhao, Jie; Luo, Jin; Hong, Yi-Fan; Wen, Sheng; Lin, Tao; He, Da-Wei; Wei, Guang-Hui; Wu, Sheng-De] Minist Educ, Key Lab Child Dev & Disorders, Chongqing 400014, Peoples R China; [Zhao, Tian-Xin] Guangzhou Med Univ, Guangzhou Women & Childrens Med Ctr, Dept Pediat Urol, Guangzhou 510620, Peoples R China; [Jiang, Li] Chongqing Med Univ, Dept Urol, Affiliated Hosp 1, Chongqing 400042, Peoples R China"

通信作者："Wu, SD (通讯作者)，Chongqing Med Univ, Childrens Hosp, Dept Urol, Chongqing 400014, Peoples R China.; Wu, SD (通讯作者)，Chongqing Key Lab Children Urogenital Dev & Tissue, Chongqing 400014, Peoples R China.; Wu, SD (通讯作者)，Natl Clin Res Ctr Child Hlth & Disorders, Chongqing 400014, Peoples R China.; Wu, SD (通讯作者)，China Int Sci & Technol Cooperat Base Child Dev &, Chongqing 400014, Peoples R China.; Wu, SD (通讯作者)，Chongqing Key Lab Pediat Chongqing, Chongqing 400014, Peoples R China.; Wu, SD (通讯作者)，Minist Educ, Key Lab Child Dev & Disorders, Chongqing 400014, Peoples R China.; Jiang, L (通讯作者)，Chongqing Med Univ, Dept Urol, Affiliated Hosp 1, Chongqing 400042, Peoples R China."

来源：ASIAN JOURNAL OF ANDROLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000882319000017

JCR分区：Q1

影响因子：2.9

年份：2022

卷号：24

期号：6

开始页：653

结束页：659

文献类型：Article

关键词：long-term; orchiectomy; pediatrics; salvage orchiopexy; testicular torsion

摘要："A retrospective cohort study was conducted at the Children's Hospital of Chongqing Medical University from November 2004 to December 2020 to investigate the long-term follow-up results after testicular torsion (TT) in children. Boys with TT were divided into the salvage orchiopexy group and the orchiectomy group, and the baseline characteristics, ultrasonographic indications, intraoperative findings, testicular volumes, and adverse events during follow-up were compared. A total of 145 cases were included in this study. Approximately 56.6% of patients who underwent salvage orchiopexy had testicular atrophy (TA), and the median testicular volume loss of the testes was 57.4%. Age less than 6 years, delayed surgery, and intraoperative poor blood supply were associated with TA in pediatric TT after orchiopexy. Most atrophied testes appeared within 3-6 months after surgery. Compared with the corresponding age-matched healthy controls, the contralateral testicular volumes were larger in the orchiopexy (P = 0.001 without TA, and P = 0.042 with TA) and orchiectomy groups (P = 0.033). The adverse events were comparable in patients with orchiectomy or orchiopexy. In summary, follow-up before 3 months after surgery may not offer sufficient clinical value, while that 3 months after surgery should be regarded as the first follow-up time for testicular monitoring. The contralateral testes of patients with TT showed compensatory hypertrophy. We suggest performing orchiectomy when torsed testes are surgically assessed as Arda grade III or inviable."

基金机构：National Natural Science Foundation of China [81873828]; Chongqing Municipal Health Commission; Innovation Program for Chongqing's Overseas Returnees [cx2019030]; Senior Medical Talents Program of Chongqing for Young and Middle-Aged

基金资助正文："This work was supported by the National Natural Science Foundation of China (No. 81873828), Chongqing Municipal Health Commission (High-Level Medical Reserved Personnel Training Project of Chongqing), the Innovation Program for Chongqing's Overseas Returnees (cx2019030), and the Senior Medical Talents Program of Chongqing for Young and Middle-Aged."