Efficacy of aerobic and resistance exercises in improving visceral adipose in patients with non-alcoholic fatty liver: a meta-analysis of randomized controlled trials

作者全名："Fu, Lixiang; Zhang, Wenyue; Ao, Yupei; Zheng, Zhongling; Hu, Huaidong"

作者地址："[Fu, Lixiang; Zhang, Wenyue; Ao, Yupei; Zheng, Zhongling; Hu, Huaidong] Second Affiliated Hosp Chongqing Med Univ, Chongqing, Peoples R China"

通信作者："Hu, HD (通讯作者)，Second Affiliated Hosp Chongqing Med Univ, Chongqing, Peoples R China."

来源：ZEITSCHRIFT FUR GASTROENTEROLOGIE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000885424900020

JCR分区：Q4

影响因子：1.3

年份：2022

卷号：60

期号：11

开始页：1644

结束页：1658

文献类型：Article

关键词：non-alcoholic fatty liver disease; aerobic exercise; resistance training; randomized controlled trial; meta-analysis

摘要："Background Non-alcoholic fatty liver disease (NAFLD) is a common chronic disease that can cause liver deterioration if insufficiently diagnosed and untreated. The verification of whether exercise interventions improve liver enzymes and lipid and glucose parameters is scant. Aim We conducted this systematic review and meta-analysis to examine the efficacy of aerobic and resistance exercise interventions in patients with NAFLD. Methods We searched the related studies in the PubMed, Embase, Cochrane Library, and Web of Science databases. We screened 1129 articles published before September 1, 2021, based on the inclusion and exclusion standards, after which 17 articles with a total of 1168 participants were finally included. The indices of liver enzymes and lipid and glucose metabolism were gathered and examined by Stata SE. Results The outcomes suggested that aerobic and resistance exercise can markedly improve the parameters of liver enzymes, blood lipids, and glucose, and especially visceral adipose tissue (weighted mean different [WMD] = -8.3 at 95% CI [-11.59 to -5.00], p < 0.0001), in patients with NAFLD. Conclusion This study demonstrated that aerobic and resistance exercises positively affect NAFLD treatment. To further quantify the effects on patients with NAFLD, a more specific and uniform exercise program should be proposed."

基金机构：National Science and Technology Major Project of China; [2017ZX10202203-007]; [2017ZX10202203-008]

基金资助正文：AcknowledgementThis research was supported by the National Science and Technology Major Project of China (2017ZX10202203-007; 2017ZX10202203-008).