Delayed Care Seeking and Outcomes of Testicular Torsion among Children during the COVID-19 Pandemic: A Systematic Review and Meta-Analysis

作者全名："Ye, Zihan; Chen, Hongsong; Liu, Xing; Wei, Guanghui"

作者地址："[Ye, Zihan; Chen, Hongsong; Liu, Xing; Wei, Guanghui] Chongqing Med Univ, Childrens Hosp, Dept Urol, Chongqing, Peoples R China; [Ye, Zihan; Chen, Hongsong; Liu, Xing; Wei, Guanghui] Minist Educ, Natl Clin Res Ctr Child Hlth & Disorders, China Int Sci & Technol Cooperat Base Child Dev &, Key Lab Child Dev & Disorders, Chongqing, Peoples R China; [Ye, Zihan; Chen, Hongsong; Liu, Xing; Wei, Guanghui] Chongqing Key Lab Children Urogenital Dev & Tissue, Chongqing, Peoples R China; [Liu, Xing] Chongqing Med Univ, Childrens Hosp, Dept Urol, 136,2nd Zhongshan Rd, Chongqing 400014, Peoples R China"

通信作者："Liu, X (通讯作者)，Chongqing Med Univ, Childrens Hosp, Dept Urol, 136,2nd Zhongshan Rd, Chongqing 400014, Peoples R China."

来源：EUROPEAN JOURNAL OF PEDIATRIC SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000886659700001

JCR分区：Q2

影响因子：1.8

年份：2022

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Review; Early Access

关键词：testicular torsion; pediatric emergency; COVID-19; orchiectomy

摘要："Introduction Since the onset of coronavirus disease 2019 (COVID-19), stay-at-home orders and fear caused by the pandemic have had a significant effect on the timing and outcomes of testicular torsion. However, the evidence was limited since the study results were inconsistent. This study aims to examine the hospitalization rates, timing, and outcomes of testicular torsion in children before and during the pandemic. Materials and Methods Using PubMed, Embase, and Google Scholar databases, we conducted a systematic search and meta-analysis of studies reporting the timing and outcomes of children admitted with testicular torsion before and during the COVID-19 pandemic. Subgroup analyses were conducted to explore possible sources of heterogeneity. Result The outcomes of 899 testicular torsion patients from eight studies were evaluated. Our study found an increased hospitalization rate for patients with testicular torsion (incidence rate ratio = 1.60, 95% confidence interval [CI]: 1.27-2.03; p = 0.001). Despite a significant increase in the duration of symptoms during the COVID-19 pandemic (weighted mean difference = 11.04, 95% CI: 2.75-19.33; p = 0.009), orchiectomy rates did not increase (odds ratio = 1.33, 95% CI: 0.85-2.10; p = 0.147). Conclusion During the COVID-19 pandemic, hospitalization rates for testicular torsion and the duration of symptoms among children increased significantly. Moreover, the rate of orchiectomy did not increase during the pandemic, indicating that pediatric emergency services have remained efficient and have prevented an increase in the number of orchiectomies performed despite pandemic-related closures and delays in transporting patients to medical care."

基金机构："National Natural Science Foundation of China [81970571]; Program for Youth Innovation in Future Medicine, Chongqing Medical University, Yuzhong, Chongqing, People's Republic of China"

基金资助正文："This work was supported by a grant from the National Natural Science Foundation of China (No. 81970571). Zihan Ye has received research support from Program for Youth Innovation in Future Medicine, Chongqing Medical University, Yuzhong, Chongqing, People's Republic of China."