"The prevalence and associated factors of prenatal depression and anxiety in twin pregnancy: a cross-sectional study in Chongqing, China"

作者全名："Zhou, Ying; Huang, Jingui; Baker, Philip N.; Liao, Bizhen; Yu, Xinyang"

作者地址："[Zhou, Ying; Liao, Bizhen; Yu, Xinyang] Chongqing Med Univ, Dept Obstet, Affiliated Hosp 1, 1 Youyilu St, Chongqing 400016, Peoples R China; [Huang, Jingui] Chongqing Univ, Dept Oncol, Canc Hosp, Chongqing 400030, Peoples R China; [Baker, Philip N.] Univ Leicester, Coll Life Sci, Leicester LE1 7RH, Leics, England"

通信作者："Liao, BZ; Yu, XY (通讯作者)，Chongqing Med Univ, Dept Obstet, Affiliated Hosp 1, 1 Youyilu St, Chongqing 400016, Peoples R China."

来源：BMC PREGNANCY AND CHILDBIRTH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000888805200003

JCR分区：Q1

影响因子：3.1

年份：2022

卷号：22

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Twin pregnancy; Depression; Anxiety; Maternal mental health; Prevalence

摘要："Background Pregnant women expecting twins are more likely to experience stress, which can lead to anxiety and depression. Our aim was to investigate the prevalence of prenatal anxiety and depressive symptoms in women with twin pregnancies and the associated factors. Methods In a cross-sectional survey, 210 women with twin pregnancies who satisfied the inclusion and exclusion criteria in two tertiary centers in Southwestern China were asked to complete a basic information form, the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS). To compare statistics with normal distribution in distinct characteristic groups, a paired t-test, and one-way ANOVA were utilized. Binary logistic step regression was used to analyze the associated factors of antenatal anxiety and depressive symptoms. Results The 210 women with twin pregnancies (age = 30.8 +/- 4.2 years) were between 7 and 37 gestational weeks (29.2 +/- 1.2 weeks), were typically well-educated (72.4% had a post-high-school degree), and reasonably affluent (88.1% were above the low-income cutoff). Among them, 34.8% had symptoms associated with clinical levels of anxiety, and 37.1% had symptoms indicating possible depression. The prevalence of co-morbid anxiety and depressive symptoms was 24.3%. Binary stepwise logistic regression analysis showed that previous health status and sleep disturbance during pregnancy were the associated factors of anxiety symptoms in women with twin pregnancies (P < 0.05), whereas age, previous health status, negative life events, and physical activity during pregnancy were the associated factors of depressive symptoms in women with twin pregnancies (P < 0.05). Conclusion About one-third of women with twin pregnancies had symptoms of anxiety or depression; these were most strongly predicted by some modifiable factors, suggesting that early preventive mind-body interventions may be a promising strategy to protect against mental health issues for women with twin pregnancies."

基金机构：Discipline Innovation Foundation in Discipline Cultivation Project of the First Affiliated Hospital of Chongqing Medical University [XKTS121]

基金资助正文："This research was supported by grants from the Discipline Innovation Foundation in Discipline Cultivation Project of the First Affiliated Hospital of Chongqing Medical University (XKTS121); the funders had no role in the design of the study, the collection, analysis, and interpretation of data, or in writing the manuscript."