Mapping global epidemiology of thyroid nodules among general population: A systematic review and meta-analysis
作者全名："Mu, Chunyang; Ming, Xin; Tian, Ye; Liu, Yang; Yao, Menglin; Ni, Yinyun; Liu, Yong; Li, Zhihui"
作者地址："[Mu, Chunyang] Sichuan Univ, West China Hosp, Dept Liver Surg, Chengdu, Peoples R China; [Mu, Chunyang] Sichuan Univ, West China Hosp, Liver Transplantat Ctr, Chengdu, Peoples R China; [Ming, Xin; Tian, Ye] Sichuan Univ, West China Hosp, Dept Ultrasound, Chengdu, Sichuan, Peoples R China; [Liu, Yang] Chongqing Med Univ, Affiliated Hosp 2, Dept Obstet & Gynecol, Chongqing, Peoples R China; [Yao, Menglin; Ni, Yinyun] Sichuan Univ, Frontiers Sci Ctr Dis Related Mol Network, Natl Clin Res Ctr Geriatr, West China Hosp,Ctr Precis Med,Precis Med Key Lab, Chengdu, Sichuan, Peoples R China; [Liu, Yong] Sichuan Univ, West China Hosp, Dept Gastroenterol Surg, Chengdu, Peoples R China; [Li, Zhihui] Sichuan Univ, West China Hosp, Dept Thyroid & Parathyroid Surg, Chengdu, Sichuan, Peoples R China; [Li, Zhihui] Sichuan Univ, West China Hosp, Frontiers Sci Ctr Dis Related Mol Network, Lab Thyroid & Parathyroid Dis, Chengdu, Sichuan, Peoples R China"
通信作者："Liu, Y (通讯作者)，Sichuan Univ, West China Hosp, Dept Gastroenterol Surg, Chengdu, Peoples R China.; Li, ZH (通讯作者)，Sichuan Univ, West China Hosp, Dept Thyroid & Parathyroid Surg, Chengdu, Sichuan, Peoples R China.; Li, ZH (通讯作者)，Sichuan Univ, West China Hosp, Frontiers Sci Ctr Dis Related Mol Network, Lab Thyroid & Parathyroid Dis, Chengdu, Sichuan, Peoples R China."
来源：FRONTIERS IN ONCOLOGY
ESI学科分类：CLINICAL MEDICINE
WOS号：WOS:000890216400001
JCR分区：Q2
影响因子：4.7
年份：2022
卷号：12
期号：
开始页：
结束页：
文献类型：Review
关键词：epidemiology; thyroid nodule; prevalence; Ultrasound; Autopsy
摘要："Introduction: An emerging public health issue is brought on by the worldwide increase of thyroid nodules (TNs). The goal of the current study is to determine the global prevalence of TNs among the general population. Methods: We screened articles published from January 2000 to May 2022. TN prevalence was calculated with the DerSimonian-Laird random effects model with arcsine transformation. Results: A total of 20,358 entries were found in our research, and 102 of them met our inclusion criteria. A total of 9,276,178 individuals have been diagnosed as TNs; the overall prevalence was 24.83% (95% CI 21.44-28.55), regardless of the diagnostic techniques. TNs have become more prevalent during 2012-2022 (29.29%) compared with 2000-2011 (21.53%, p = 0.02). In addition, we discovered that women (36.51%) were more likely to have TNs than men (23.47%, p < 0.01). Interestingly, we found that obesity was correlated with the prevalence of TNs. Additionally, age-specific-stratified TN prevalence was found in our results. Discussion: This meta-analysis shows that, regardless of country development and economic status, TNs are spreading more widely over the world. Our findings showed a strong correlation between rising TN prevalence and older age, female sex, and elevated weight. To stop the TN epidemic from spreading over the world, increased awareness, the understanding of the disease, and quick action are required."
基金机构："China Postdoctoral Science Foundation [2021M702340]; Sichuan Science and Technology Program [2021ZYCD016, 2020YFS0573, 2022NSFSC1441]; Key Research and Development Program of Science and Technology Department of Sichuan Province [2019YFS0360]"
基金资助正文："This research is supported by the fellowship of China Postdoctoral Science Foundation (2021M702340), Sichuan Science and Technology Program (2021ZYCD016, 2020YFS0573, 2022NSFSC1441), Key Research and Development Program of Science and Technology Department of Sichuan Province 2019YFS0360."
