Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice

作者全名："Nalisa, David Lubasi; Moneruzzaman, Md.; Changwe, Geoffrey J.; Mobet, Youchaou; Li, Li Ping; Ma, Yu Jin; Jiang, Hong Wei"

作者地址："[Nalisa, David Lubasi; Li, Li Ping; Ma, Yu Jin; Jiang, Hong Wei] Henan Univ Sci & Technol, Affiliated Hosp 1, Endocrine & Metab Dis Ctr, Dept Metab & Endocrinol, Luoyang 471003, Peoples R China; [Nalisa, David Lubasi; Li, Li Ping; Ma, Yu Jin; Jiang, Hong Wei] Henan Univ Sci & Technol, Coll Clin Med, Luoyang 471003, Peoples R China; [Nalisa, David Lubasi; Li, Li Ping; Ma, Yu Jin; Jiang, Hong Wei] Med Key Lab Hereditary Rare Dis Henan, Luoyang 471003, Peoples R China; [Nalisa, David Lubasi; Li, Li Ping; Ma, Yu Jin; Jiang, Hong Wei] Luoyang Sub Ctr Natl Clin Res Ctr Metab Dis, Luoyang 471003, Peoples R China; [Moneruzzaman, Md.] Shandong Univ, Qilu Hosp, Dept Rehabil Med & Physiotherapy, Jinan 250012, Shandong, Peoples R China; [Changwe, Geoffrey J.] Natl Heart Hosp, Dept Cardiovasc & Thorac Surg, Off Airport Rd, Lusaka 10101, Zambia; [Mobet, Youchaou] Chongqing Med Univ, Affiliated Hosp 3, Dept Obstet & Gynecol, Chongqing 401120, Peoples R China"

通信作者："Jiang, HW (通讯作者)，Henan Univ Sci & Technol, Affiliated Hosp 1, Endocrine & Metab Dis Ctr, Dept Metab & Endocrinol, Luoyang 471003, Peoples R China.; Jiang, HW (通讯作者)，Henan Univ Sci & Technol, Coll Clin Med, Luoyang 471003, Peoples R China.; Jiang, HW (通讯作者)，Med Key Lab Hereditary Rare Dis Henan, Luoyang 471003, Peoples R China.; Jiang, HW (通讯作者)，Luoyang Sub Ctr Natl Clin Res Ctr Metab Dis, Luoyang 471003, Peoples R China."

来源：JOURNAL OF DIABETES RESEARCH

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000899228600001

JCR分区：Q2

影响因子：4.3

年份：2022

卷号：2022

期号：　

开始页：　

结束页：　

文献类型：Review

关键词：　

摘要："Diabetic foot ulcers are associated with increases in limb amputation, morbidity, and mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We presented available remedies by conducting a literature review on the application, safety, and efficacy of stem cell therapy. Relevant literature, including randomized control trials and article journals, was obtained from reputable search engines (PubMed, Scopus, and Web of Science). We analyzed five credible cohorts, with variable sources of stem cells, in a total of 216 participants, 151 males and 65 females, age (mean & PLUSMN;SD) of 64.5 & PLUSMN;9.6 years. With an average success of 86.41% in all Wagner-II lesions, mesenchymal SCA (stem cell application) is safe and effective, hence can significantly prevent limb amputation."

基金机构：Medical and Health Research Project in Luoyang; Construction Project of Improving Medical Service Capacity of Provincial Medical Institutions in Henan Province; Science and Technology Research Project in Henan Province; [2001027A]; [1920008A]; [2017-51]; [222102310008]

基金资助正文："AcknowledgmentsThis work was supported by the Medical and Health Research Project in Luoyang (Nos. 2001027A and 1920008A), the Construction Project of Improving Medical Service Capacity of Provincial Medical Institutions in Henan Province (No. 2017-51), and the Science and Technology Research Project in Henan Province (No. 222102310008)."