Value of abdominal ultrasonography in predicting intestinal resection for premature infants with necrotizing enterocolitis

作者全名："Chen, Jingyu; Mu, Fangting; Gao, Kai; Yan, Chengwei; Chen, Gongli; Guo, Chunbao"

作者地址："[Chen, Jingyu; Mu, Fangting] Chongqing Med Univ, Childrens Hosp, Dept Ultrasound, Chongqing, Peoples R China; [Gao, Kai; Chen, Gongli; Guo, Chunbao] Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat, 120 Longshan Rd, Chongqing 401147, Peoples R China; [Yan, Chengwei] Chongqing Univ, Dept Pediat Gen Surg, Gorges Hosp 3, Chongqing, Peoples R China; [Chen, Jingyu; Mu, Fangting; Guo, Chunbao] Chongqing Med Univ, Minist Educ Key Lab Child Dev & Disorders, Chongqing, Peoples R China; [Chen, Gongli; Guo, Chunbao] Chongqing Hlth Ctr Women & Children, Dept Pediat, Chongqing, Peoples R China"

通信作者："Guo, CB (通讯作者)，Chongqing Med Univ, Women & Childrens Hosp, Dept Pediat, 120 Longshan Rd, Chongqing 401147, Peoples R China."

来源：BMC GASTROENTEROLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000899884800001

JCR分区：Q3

影响因子：2.4

年份：2022

卷号：22

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Necrotizing enterocolitis; Abdominal ultrasonography; Abdominal radiograph; Intestinal resection

摘要："Background: Abdominal ultrasonography (AUS) has been suggested to be valuable in the early detection of necrotizing enterocolitis (NEC). Objective: Here, we intended to assess the efficiency of abdominal ultrasound in terms of predicting bowel resection in infants with NEC. Methods: From January 2018 to March 2021, 164 hospitalized children with NEC who underwent surgical management were enrolled. The enrolled infants were separated into two groups according to whether they underwent bowel resection. We reviewed the clinical data, as well as dynamic sonographic and abdominal radiographic (AR) parameters. The potential performance of AUS parameters was identified and compared with that of AR using a logistic regression analysis and receiver operating characteristic (ROC) curve analysis. Results: Several parameters were detected to be statistically significant in predicting the occurrence of bowel resection, including thick to thin transformation [p < 0.001, odds ratios (OR), 4.38; 95% confidence interval (CI) 2.26-8.52], absence of peristalsis certain areas (p = 0.001, OR, 2.99; 95% CI 1.53-5.86), absence of bowel wall perfusion (p < 0.001, OR 10.56; 95% CI 5.09-21.90), and portal venous gas (p = 0.016, OR, 2.21; 95% CI 1.12-4.37). Furthermore, the ROC curve analysis showed significant differences (p = 0.0021) in the area under the receiver operating curve (AUROC) for the logistic models of AUS (AUROC: 0.755, 95% CI 0.660-0.849) and AR (AUROC: 0.693, 95% CI 0.597-0.789) for the prediction of intestinal resection. Conclusions: A dynamic AUS examination play an important role to indicate the potential for bowel loss during the surgery."

基金机构："chongqing children's hospital Foundation; National Natural Science Foundation of China [lcyj2015-2]; Key Project of the Chongqing Natural Science Foundation (CSTC) [30973440, 30770950]; Chongqing Health Planning Commission of Research Fund [2008BA0021, cstc2012jjA0155]; [2016MSXM044]"

基金资助正文："This study was supported by Grants from the chongqing children's hospital Foundation (lcyj2015-2) and National Natural Science Foundation of China (Nos: 30973440 and 30770950) in the design of the study; the Key Project of the Chongqing Natural Science Foundation (CSTC, 2008BA0021, cstc2012jjA0155) for collection, analysis, and interpretation of data; and the Chongqing Health Planning Commission of Research Fund (No: 2016MSXM044) in writing the manuscript."