Off-Hour Admission Is Associated with Poor Outcome in Patients with Intracerebral Hemorrhage

作者全名："Akram, Muhammad Junaid; Lv, Xinni; Deng, Lan; Li, Zuoqiao; Yang, Tiannan; Yin, Hao; Wu, Xiaofang; Pu, Mingjun; Chen, Chu; Zhao, Libo; Li, Qi"

作者地址："[Akram, Muhammad Junaid; Lv, Xinni; Deng, Lan; Li, Zuoqiao; Yang, Tiannan; Yin, Hao; Wu, Xiaofang; Pu, Mingjun; Chen, Chu; Li, Qi] Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing 400016, Peoples R China; [Zhao, Libo] Chongqing Med Univ, Dept Neurol, Yongchuan Hosp, Chongqing 402160, Peoples R China; [Zhao, Libo; Li, Qi] Chongqing Key Lab Cerebrovascular Dis Res, Chongqing 402160, Peoples R China; [Li, Qi] Anhui Med Univ, Dept Neurol, Affiliated Hosp 2, Hefei 230601, Peoples R China"

通信作者："Li, Q (通讯作者)，Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing 400016, Peoples R China.; Zhao, LB (通讯作者)，Chongqing Med Univ, Dept Neurol, Yongchuan Hosp, Chongqing 402160, Peoples R China.; Zhao, LB; Li, Q (通讯作者)，Chongqing Key Lab Cerebrovascular Dis Res, Chongqing 402160, Peoples R China.; Li, Q (通讯作者)，Anhui Med Univ, Dept Neurol, Affiliated Hosp 2, Hefei 230601, Peoples R China."

来源：JOURNAL OF CLINICAL MEDICINE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000910266800001

JCR分区：Q1

影响因子：3.9

年份：2023

卷号：12

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：stroke; intracerebral hemorrhage; off-hour; outcome

摘要："The mortality of stroke increases on weekends and during off-hour periods. We investigated the effect of off-hour admission on the outcomes of intracerebral hemorrhage (ICH) patients. We retrospectively analyzed a prospective cohort of ICH patients, admitted between January 2017 and December 2019 at the First Affiliated Hospital of Chongqing Medical University. Acute ICH within 72 h after onset with a baseline computed tomography and 3-month follow-up were included in our study. Multivariable logistic regression analysis was performed for calculating the odds ratios (OR) and 95% confidence interval (CI) for the outcome measurements. Of the 656 participants, 318 (48.5%) were admitted during on-hours, whereas 338 (51.5%) were admitted during off-hours. Patients with a poor outcome had a larger median baseline hematoma volume, of 27 mL (interquartile range 11.1-53.2 mL), and a lower median time from onset to imaging, of 2.8 h (interquartile range 1.4-9.6 h). Off-hour admission was significantly associated with a poor functional outcome at 3 months, after adjusting for cofounders (adjusted OR 2.17, 95% CI 1.35-3.47; p = 0.001). We found that patients admitted during off-hours had a higher risk of poor functional outcomes at 3 months than those admitted during working hours."

基金机构："National Natural Science Foundation of China [82071337]; National Key R&D Program of China [2018YFC1312200, 2018YFC1312203]; Chongqing High-End Young Investigator Project [2019GDRC005]; Science and Technology Innovation Project of the ""Chengdu-Chongqing Economic Circle"" [KJCXZD2020019]; Chongqing Innovation Support Program for Returned Overseas Chinese Scholars [cx2020002]; Chongqing Science Fund for Distinguished Young Scholars [cstc2021jcyj-jqX0029]"

基金资助正文："This study was supported by the National Natural Science Foundation of China (Grant No. 82071337), the National Key R&D Program of China (Grant Nos. 2018YFC1312200 and 2018YFC1312203), the Chongqing High-End Young Investigator Project (Grant No. 2019GDRC005), the Science and Technology Innovation Project of the ""Chengdu-Chongqing Economic Circle"" (Grant No. KJCXZD2020019), the Chongqing Innovation Support Program for Returned Overseas Chinese Scholars (Grant No. cx2020002), and the Chongqing Science Fund for Distinguished Young Scholars (Grant No. cstc2021jcyj-jqX0029)."