"Possible transmission of COVID-19 epidemic by a dog as a passive mechanical carrier of SARS-CoV-2, Chongqing, China, 2022"

作者全名："Zhou, Chunbei; Wu, Ailin; Ye, Sheng; Zhou, Zongliang; Zhang, Hongjun; Zhao, Xiyou; Wang, Ya; Wu, Huan; Ruan, Dandan; Chen, Shuang; Tang, Wenge; Xu, Shibin; Li, Qin; Su, Kun"

作者地址："[Zhou, Chunbei; Wu, Ailin; Ye, Sheng; Chen, Shuang; Tang, Wenge; Li, Qin; Su, Kun] Chongqing Ctr Dis Control & Prevent, 8 Changjiang 2nd Rd, Chongqing 400042, Peoples R China; [Zhou, Chunbei] Third Mil Med Univ, Army Med Univ, Chongqing, Peoples R China; [Ye, Sheng; Chen, Shuang] Chongqing Municipal Key Lab High Pathogen Microbe, Chongqing, Peoples R China; [Zhou, Zongliang; Zhang, Hongjun; Wang, Ya; Wu, Huan; Ruan, Dandan; Xu, Shibin] Yongchuan Dist Ctr Dis Control & Prevent, 471 Longteng Rd, Chongqing 402160, Peoples R China; [Zhao, Xiyou] Community Hlth Serv Ctr, Zhongshan Rd, Chongqing, Peoples R China; [Su, Kun] Chongqing Med Univ, Sch Publ Hlth & Management, Chongqing, Peoples R China; [Su, Kun] Chongqing Publ Hlth Med Ctr, Chongqing, Peoples R China"

通信作者："Li, Q; Su, K (通讯作者)，Chongqing Ctr Dis Control & Prevent, 8 Changjiang 2nd Rd, Chongqing 400042, Peoples R China.; Xu, SB (通讯作者)，Yongchuan Dist Ctr Dis Control & Prevent, 471 Longteng Rd, Chongqing 402160, Peoples R China."

来源：JOURNAL OF MEDICAL VIROLOGY

ESI学科分类：MICROBIOLOGY

WOS号：WOS:000911465200326

JCR分区：Q1

影响因子：12.7

年份：2023

卷号：95

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：COVID-19; Omicron; outbreak; SARS-CoV-2; transmission

摘要："An outbreak of coronavirus disease 2019 (COVID-19) was reported in Yongchuan district of Chongqing, China in March 2022, while the source was unknown. We aimed to investigate the origin and transmission route of the virus in the outbreak. We conducted field investigations for all cases and collected their epidemiological and clinical data. We performed gene sequencing and phylogenetic analysis for the cases, and draw the epidemic curve and the case relationship chart to analyze interactions and possible transmission mode of the outbreak. A total of 11 cases of COVID-19, including 5 patients and 6 asymptomatic cases were laboratory-confirmed in the outbreak. The branch of the virus was Omicron BA.2 which was introduced into Yongchuan district by a traveler in early March. Patient F and asymptomatic case G had never contact with other positive-infected individuals, but close contact with their pet dog that sniffed the discarded cigarette butts and stepped on the sputum of patient B. Laboratory test results showed that the dog hair and kennel were positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and the 10 isolates were highly homologous to an epidemic strain in a province of China. The investigation suggested that the contaminated dog by SARS-CoV-2 can act as a passive mechanical carrier of the virus and might transmit the virus to humans through close contact. Our findings suggest that during the COVID-19 pandemic, increasing hygiene measures and hand washing after close contact with pets is essential to minimize the risk of community spread of the virus."

基金机构："Key Research and Development Project in the Health Field of Chongqing [CSTC2021jscx-gksb-N0003]; Science-Health Joint Medical Scientific Research Project of Chongqing [2020FYYX234, 2020FYYX154, 2020FYYX120]"

基金资助正文："The authors thank all participants for sharing information necessary for this outbreak investigation and management. This study was supported by the Key Research and Development Project in the Health Field of Chongqing (CSTC2021jscx-gksb-N0003), Science-Health Joint Medical Scientific Research Project of Chongqing (Grant Number 2020FYYX234, 2020FYYX154, 2020FYYX120)."