Obstetric anesthesia clinic childbirth course combined with labor epidural analgesia is associated with a decreased risk of postpartum depression : a prospective cohort study

作者全名："Tong, Shanshan; Rao, Chuanhua; Min, Su; Li, Hua; Quan, Dongqun; Chen, Daping; Zhu, Yuanmao"

作者地址："[Tong, Shanshan; Min, Su] Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, 1 Youyi Rd, Chongqing 400016, Peoples R China; [Rao, Chuanhua] Jiangjin Cent Hosp Chongqing, Dept Anesthesiol, 725 Jiangzhou Ave,Dingshan St, Chongqing, Peoples R China; [Li, Hua; Quan, Dongqun; Chen, Daping] Jiangjin Cent Hosp Chongqing, Dept Obstet, Chongqing, Peoples R China; [Zhu, Yuanmao] Jiangjin Cent Hosp Chongqing, Dept Pain, Chongqing, Peoples R China"

通信作者："Min, S (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Anesthesiol, 1 Youyi Rd, Chongqing 400016, Peoples R China."

来源：BMC ANESTHESIOLOGY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000912194500001

JCR分区：Q2

影响因子：2.2

年份：2022

卷号：22

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：Postpartum depression (PPD); Labor epidural analgesia; Childbirth course; Edinburgh postpartum depression scale (EPDS)

摘要："Background: Postpartum depression (PPD) is a serious complication commonly seen in postnatal women. In this paper, an investigation was conducted to see if obstetric anesthesia clinic childbirth course combined with labor epidural analgesia (LEA) was associated with a decreased risk of PPD. Methods: Six hundred fifty-five nulliparous women were enrolled in this prospective cohort study. The parturients were divided into 4 groups, with Group C being the control group, Group AC received the obstetric anesthesia clinic childbirth course only, Group LEA received LEA only, and Group AC + LEA received both the obstetric anesthesia clinic childbirth course and LEA. Maternal and neonatal variables in the perinatal period were recorded. PPD at 6 weeks was assessed using the Chinese version of the Edinburgh Postpartum Depression Scale (EPDS), where a score >= 10 is the threshold for PPD. Multivariate logistic regression analysis was performed to assess the association between obstetric anesthesia clinic childbirth course combined with LEA and postpartum depression. Results: A total of 124 maternities had EPDS >= 10 points, the incidence of PPD was 18.9%.The incidence of PPD and EPDS scores were significantly lower in Group AC + LEA than in Group C (12.1% vs 26.8%, P < 0.05; 6 (5, 7) vs 7 (5, 11), P < 0.05). Received an anesthesia clinic childbirth course combined with LEA was associated with a decreased risk of PPD (OR 0.273, 95% CI, 0.100-0.743, P = 0.013). Multivariate logistic regression analysis identified 5 other independent factors for PPD, including maternal SAS score in the delivery room, W-DEQ score in the delivery room, living in a confinement center, EPDS score at 1st week postpartum and perinatal care satisfaction . Conclusions: Received an obstetrics anesthesia clinic childbirth course combined with LEA for nulliparous women with a single term cephalic pregnancy was associated with a decreased risk of PPD at 6 weeks."

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