"Epidemiological Characteristics and Factors Associated with Cure of Leprosy in Chongqing, China, from 1949 to 2019"

作者全名："Wang, Yunna; Xiao, Dayong; Wu, Mingyue; Qing, Liyuan; Yang, Tong; Xiao, Peng; Deng, Dan"

作者地址："[Wang, Yunna; Qing, Liyuan; Yang, Tong; Deng, Dan] Chongqing Med Univ, Sch Publ Hlth, 1 Med Coll Rd, Chongqing 400016, Peoples R China; [Xiao, Dayong; Xiao, Peng] Chongqing Ctr Dis Control & Prevent, Chongqing, Peoples R China; [Wu, Mingyue] Sichuan Univ, West China Hosp, Informat Ctr, Chengdu, Peoples R China"

通信作者："Deng, D (通讯作者)，Chongqing Med Univ, Sch Publ Hlth, 1 Med Coll Rd, Chongqing 400016, Peoples R China."

来源：AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000924080500028

JCR分区：Q1

影响因子：3.3

年份：2023

卷号：108

期号：1

开始页：165

结束页：173

文献类型：Article

关键词：　

摘要："Chongqing is one of the focuses of leprosy control in China. Although leprosy control in Chongqing has achieved remarkable results over the years, there are also some problems, such as recurrent epidemics and insufficient early detection in some areas. The aim of this study was to analyze the epidemiological characteristics of leprosy in Chong-qing, from 1949 to 2019 and explore the potential factors sociated with cure of leprosy to provide a basis for improving leprosy prevention and treatment strategies in Chongqing. Epidemiological indicators such as incidence and prevalence rates were used to evaluate the prevalence of leprosy. The epidemiological characteristics and control situation of leprosy in patients were analyzed using demographic characteristics, diagnosis, and treatment. Survival analysis was conducted to explore factors associated with the cure of leprosy. From 1949 to 2019, 3,703 cases of leprosy were registered in Chongqing. The incidence of leprosy in the city peaked at 0.853/105 in 1960 and remained below 0.100/105 after 2003. The number of high incidence areas decreased significantly, but they were mainly concentrated in the northeast and south-east regions. The early detection rate increased yearly from 1949 to 2019, and the rate of grade 2 disability ranged from 38.2% to 21.7%, with a fluctuating downward trend after 1960. Male, young age, employment as a farmer, delayed diag-nosis, and multibacillary leprosy were risk factors for leprosy cure. Chongqing should continue to strengthen leprosy moni-toring to improve the early detection of leprosy and focus on sociated risk factors to carry out multiple strategies."

基金机构：Chongqing Basic Research and Frontier Exploration Project [cstc2018jcyjA0135]

基金资助正文：Financial support: Publication of this article was funded by Chongqing Basic Research and Frontier Exploration Project (cstc2018jcyjA0135) .