Chinese Expert Consensus on Immunotherapy for Hepatocellular Carcinoma (2021 Edition)

作者全名:"Yang, Yu; Sun, Juxian; Wu, Mengchao; Lau, Wan Yee; Zheng, Shusen; Wang, Xue-Hao; Chen, Xiaoping; Fan, Jia; Dong, Jiahong; Cai, Jianqiang; Chen, Minshan; Chen, Yongjun; Cheng, Zhangjun; Dai, Chaoliu; Shan, Jianzhen; Du, Cheng-You; Fang, Chihua; Hu, Heping; Ji, Zhili; Jia, Weidong; Li, Gong; Li, Jing; Li, Jiangtao; Liu, Chang; Liu, Fubao; Ma, Yong; Mao, Yilei; Niu, Zuoxing; Shen, Jie; Shi, Jie; Shi, Xuetao; Song, Wenjie; Sun, Hui-Chuan; Tan, Guang; Tao, Ran; Wang, Xiaohu; Wen, Tianfu; Wu, Liqun; Xia, Jinglin; Xiang, Bang-De; Yan, Maolin; Ying, Mingang; Zhang, Ling; Zhang, Xuewen; Zeng, Zhao Chong; Zhang, Yubao; Zhang, Zhiwei; Zhou, Jie; Zhou, Cuncai; Zhou, Jun; Zhou, Ledu; Zhou, Xinmin; Zhu, Ji; Zhu, Zhenyu; Zhang, Qi; Li, Qiu; Cheng, Shuqun"

作者地址:"[Yang, Yu; Li, Qiu] Sichuan Univ, West China Hosp, Canc Ctr, Dept Med Oncol, Chengdu, Peoples R China; [Sun, Juxian; Wu, Mengchao; Lau, Wan Yee; Shi, Jie; Cheng, Shuqun] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepat Surg 6, Shanghai, Peoples R China; [Lau, Wan Yee] Chinese Univ Hong Kong, Fac Med, Hong Kong, Peoples R China; [Zheng, Shusen] Shulan Hangzhou Hosp, Dept Hepatobiliary & Pancreat Surg, Hangzhou, Peoples R China; [Wang, Xue-Hao] Nanjing Med Univ, Hepatobiliary Ctr, Affiliated Hosp 1, Nanjing, Peoples R China; [Chen, Xiaoping] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Hepat Surg Ctr, Wuhan, Peoples R China; [Fan, Jia; Sun, Hui-Chuan] Fudan Univ, Dept Liver Surg & Transplantat, Liver Canc Inst,Minist Educ, Zhongshan Hosp,Key Lab Carcinogenesis & Canc Inva, Shanghai, Peoples R China; [Dong, Jiahong] Tsinghua Univ, Beijing Tsinghua Changgung Hosp BTCH, Sch Clin Med, Dept Hepatobiliary & Pancreas Surg, Beijing, Peoples R China; [Cai, Jianqiang] Chinese Acad Med Sci, Canc Hosp, Dept Hepatobiliary Surg, Beijing, Peoples R China; [Chen, Minshan] Sun Yat Sen Univ Canc Ctr, Dept Hepatobiliary Surg, Guangzhou, Peoples R China; [Chen, Yongjun] Shanghai Jiao Tong Univ, Ruijin Hosp, Dept Hepatobiliary Surg, Sch Med, Shanghai, Peoples R China; [Cheng, Zhangjun] Southeast Univ, Zhongda Hosp, Dept Hepatobiliary Surg, Nanjing, Peoples R China; [Dai, Chaoliu] China Med Univ, Affiliated Shengjing Hosp, Dept Hepatobiliary & Spleenary Surg, Shenyang, Peoples R China; [Shan, Jianzhen] Zhejiang Univ, Dept Med Oncol, Sch Med, Affiliated Hosp 1, Hangzhou, Peoples R China; [Du, Cheng-You] Chongqing Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Chongqing, Peoples R China; [Fang, Chihua] First Mil Med Univ, Zhujiang Hosp, Dept Hepatobiliary Surg, Guangzhou, Peoples R China; [Hu, Heping] Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Gastroenterol, Shanghai, Peoples R China; [Ji, Zhili] Capital Med Univ, Beijing Anzhen Hosp, Dept Gen Surg, Beijing, Peoples R China; [Jia, Weidong] Univ Sci & Technol China, USTC, Dept Gen Surg, Affiliated Hosp 1, Hefei, Peoples R China; [Li, Gong] Tsinghua Univ, Beijing Tsinghua Changgung Hosp BTCH, Sch Clin Med, Dept Radiat Oncol, Beijing, Peoples R China; [Li, Jing] Third Mil Med Univ, Xinqiao Hosp, Dept Hepatobiliary Surg, Chongqing, Peoples R China; [Li, Jiangtao] Zhejiang Univ, Dept Hepatobiliary & Pancreat Surg, Affiliated Hosp 2, Sch Med, Hangzhou, Peoples R China; [Liu, Chang] Xi An Jiao Tong Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Xian, Peoples R China; [Liu, Fubao] Anhui Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Hefei, Peoples R China; [Ma, Yong] Harbin Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Harbin, Peoples R China; [Mao, Yilei] PUMC & Chinese Acad Med Sci, Peking Union Med Coll PUMC Hosp, Dept Liver Surg, Beijing, Peoples R China; [Niu, Zuoxing] Shandong Canc Hosp, Dept Gastroenterol, Jinan, Peoples R China; [Shen, Jie] Nanjing Univ, Canc Ctr, Dept Med Oncol, Nanjing Drum Tower Hosp,Med Coll, Nanjing, Peoples R China; [Shi, Xuetao] Shandong Canc Hosp, Dept Hepatobiliary Surg, Jinan, Peoples R China; [Song, Wenjie] Air Force Med Univ, Xijing Hosp, Dept Hepatobiliary Surg, Xian, Peoples R China; [Tan, Guang] Dalian Med Univ, Dept Hepatobiliary Surg, Affiliated Hosp 1, Dalian, Peoples R China; [Tao, Ran] Zhejiang Prov Peoples Hosp, Dept Hepatobiliary Surg, Hangzhou, Peoples R China; [Wang, Xiaohu] Gansu Canc Hosp, Dept Radiat Oncol, Lanzhou, Peoples R China; [Wen, Tianfu] Sichuan Univ, West China Hosp, Ctr Liver Transplantat, Dept Liver Surg, Chengdu, Peoples R China; [Wu, Liqun] Affiliated Hosp Qingdao Univ, Div Hepatobiliary Pancreat Surg, Qingdao, Peoples R China; [Xia, Jinglin] Fudan Univ, Zhongshan Hosp, Liver Canc Inst, Shanghai, Peoples R China; [Xiang, Bang-De] Guangxi Med Univ, Dept Hepatobiliary Surg, Canc Hosp, Nanning, Peoples R China; [Yan, Maolin] Fujian Prov Hosp, Dept Hepatobiliary & Pancreat Surg, Fuzhou, Peoples R China; [Ying, Mingang] Fujian Med Univ, Fujian Prov Canc Hosp, Dept Abdominal Surg, Teaching Hosp, Fuzhou, Peoples R China; [Zhang, Ling] Zhengzhou Univ, Dept Hepatobiliary Surg, Canc Hosp, Zhengzhou, Peoples R China; [Zhang, Xuewen] Second Hosp Jilin Univ, Dept Hepatobiliary & Pancreas Surg, Changchun, Peoples R China; [Zeng, Zhao Chong] Fudan Univ, Zhongshan Hosp, Dept Radiat Oncol, Shanghai, Peoples R China; [Zhang, Yubao] Harbin Med Univ, Dept Hepatobiliary Surg, Canc Hosp, Harbin, Peoples R China; [Zhang, Zhiwei] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Surg, Wuhan, Peoples R China; [Zhou, Jie] Southern Med Univ, Nanfang Hosp, Dept Hepatobiliary Surg, Guangzhou, Peoples R China; [Zhou, Cuncai] Jiangxi Prov Canc Hosp, Dept Hepatobiliary Surg, Nanchang, Jiangxi, Peoples R China; [Zhou, Jun] Beijing Canc Hosp, Dept Med Oncol, Beijing, Peoples R China; [Zhou, Ledu] Cent South Univ, Xiangya Hosp, Dept Gen Surg, Changsha, Peoples R China; [Zhou, Xinmin] Air Force Med Univ, Xijing Hosp, Dept Gastroenterol, Xian, Peoples R China; [Zhu, Ji] Chinese Acad Sci, Dept Radiat Oncol, Canc Hosp Univ, Hangzhou, Peoples R China; [Zhu, Zhenyu] Peoples Liberat Army Gen Hosp, Dept Hepatobiliary Surg, Med Ctr 5, Beijing, Peoples R China; [Zhang, Qi] Sun Yat Sen Univ, Dept Hepatobiliary Surg, Affiliated Hosp 3, Guangzhou, Peoples R China"

通信作者:"Li, Q (通讯作者),Sichuan Univ, West China Hosp, Canc Ctr, Dept Med Oncol, Chengdu, Peoples R China.; Cheng, SQ (通讯作者),Second Mil Med Univ, Eastern Hepatobiliary Surg Hosp, Dept Hepat Surg 6, Shanghai, Peoples R China."

来源:LIVER CANCER

ESI学科分类:CLINICAL MEDICINE

WOS号:WOS:000924586800003

JCR分区:Q1

影响因子:13.8

年份:2022

卷号:11

期号:6

开始页:511

结束页:526

文献类型:Review

关键词:Hepatocellular carcinoma; Immune checkpoint inhibitors; Consensus

摘要:"Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies in China. Most HCC patients are first diagnosed at an advanced stage, and systemic treatments are the mainstay of treatment. Summary: In recent years, immune checkpoint inhibitors have made a breakthrough in the systemic treatment of middle-advanced HCC, breaking the single therapeutic pattern of molecular-targeted agents. To better guide the clinical treatment for effective and safe use of immunotherapeutic drugs, the Chinese Association of Liver Cancer and Chinese Medical Doctor Association has gathered multidisciplinary experts and scholars in relevant fields to formulate the ""Chinese Clinical Expert Consensus on Immunotherapy for Hepatocellular Carcinoma (2021)"" based on current clinical studies and clinical medication experience for reference in China. Key Messages: The consensus contained 17 recommendations, including the preferred regimen for first- and second-line immunotherapy, evaluation and monitoring before/during/after treatment, management of complications, precautions for special patients, and potential population for immunotherapy. (c) 2022 The Author(s). Published by S. Karger AG, Basel"

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