The influence of different previous cancer histories on the diagnostic efficacy of Lung Imaging Reporting and Data System

作者全名："Song, Feipeng; Fu, Binjie; Liu, Xiangling; Liu, Mengxi; Lv, Fajin"

作者地址："[Song, Feipeng; Fu, Binjie; Liu, Xiangling; Liu, Mengxi; Lv, Fajin] Chongqing Med Univ, Affiliated Hosp 1, Dept Radiol, 1 YouYi Rd, Chongqing 400010, Peoples R China; [Song, Feipeng] Shanxi Med Univ, Hosp 2, Dept Radiol, Taiyuan, Peoples R China"

通信作者："Lv, FJ (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Radiol, 1 YouYi Rd, Chongqing 400010, Peoples R China."

来源：QUANTITATIVE IMAGING IN MEDICINE AND SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:000945813100001

JCR分区：Q2

影响因子：2.8

年份：2023

卷号：　

期号：　

开始页：　

结束页：　

文献类型：Article; Early Access

关键词：Pulmonary nodule; computed tomography; X-ray; previous malignancy; Lung-RADS

摘要："Background: For lung cancer screening in patients with previous malignant tumors, Lung Imaging Reporting and Data System (Lung-RADS) and other lung cancer screening tools are controversial in terms of requirements for the previous cancer history. This study investigated the effect of the length and type of malignancy history on the diagnostic efficacy of Lung Imaging Reporting and Data System (Lung-RADS) 2022 in pulmonary nodules (PNs).Methods: Chest computed tomography and clinical data of PNs in patients with a history of cancer who underwent surgical resection in The First Affiliated Hospital of Chongqing Medical University from January 1, 2018, to November 30, 2021, were retrospectively collected and evaluated based on Lung-RADS. All PNs were divided into 2 groups: the prior lung cancer (PLC) and the prior extrapulmonary cancer (PEPC) groups. Each group was divided into the >_5 years and <5 years groups based on the duration of cancer history. The diagnostic agreement of Lung-RADS was evaluated based on the pathological diagnosis of nodules after operation. The diagnostic agreement rate (AR) of Lung-RADS and the composition ratios of different types between different groups were calculated and compared.Results: A total of 451 patients with 565 PNs were included in this study. These patients were divided into the PLC group (<5 years: 135 cases, 175 PNs; >_5 years: 9 cases, 12 PNs) and the PEPC group (<5 years: 219 cases, 278 PNs; >_5 years: 88 cases, 100 PNs). The diagnostic AR of partial solid nodules (93.0%; 95% CI: 88.7-97.2%) and solid nodules (88.1%; 95% CI: 84.1-92.1%) was close (P=0.13), while both were higher than that of the pure ground-glass nodules (24.0%; 95% CI: 17.5-30.4%; all P values <0.001). Within 5 years, the composition ratio of PNs and the diagnostic AR (PLC: 58.9%, 95% CI: 51.5-66.2%; PEPC: 76.6%, 95% CI: 71.6-81.6%) between the PLC and PEPC groups were all different (all P values <0.001), and the others (composition ratio of PNs & the diagnostic AR: PLC (>_5 years) vs. PEPC (>_5 years); PLC (<5 years) vs. PLC (>_5 years); PEPC (<5 years) vs. PEPC (>_5 years)) were similar (all P values >0.05; range: 0.10-0.93).Conclusions: The length of prior cancer history may affect the diagnostic agreement of Lung-RADS, especially for patients with prior lung cancer within 5 years."

基金机构：Technology Innovation and Application Development Special Key Project of Chongqing [CSTC2021jscx-ksbN 0030]; Science-Health Joint Medical Scientific Research Project of Chongqing [2022ZDXM006]

基金资助正文：Funding: This research was supported by the Technology Innovation and Application Development Special Key Project of Chongqing (No. CSTC2021jscx-ksbN 0030) and the Science-Health Joint Medical Scientific Research Project of Chongqing (No. 2022ZDXM006) .