Combined evaluation of audiology examination and self-reported symptoms in patients with hyperacusis
作者全名："Huang, Yu; Xiang, Tao; Jiang, Fan; Ren, Jing; Xu, Tao; Lai, Dan"
作者地址："[Huang, Yu; Jiang, Fan; Ren, Jing; Xu, Tao; Lai, Dan] Southwest Med Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, 25 TaiPing St, Luzhou 646000, Sichuan, Peoples R China; [Xiang, Tao] Chongqing Med Univ, Affiliated Hosp 2, Dept Otolaryngol Head & Neck Surg, Chongqing, Peoples R China"
通信作者："Lai, D (通讯作者)，Southwest Med Univ, Affiliated Hosp, Dept Otolaryngol Head & Neck Surg, 25 TaiPing St, Luzhou 646000, Sichuan, Peoples R China."
摘要："To investigate the application of combined audiological examination and a self-reported symptoms survey in the evaluation of hyperacusis. Patients who visited the outpatient department of Otolaryngology Head and Neck Surgery and Otological medicine, Affiliated Hospital of Southwest Medical University, from January 2019 to March 2021 were divided into a hyperacusis group and a normal control group. We measured the loudness discomfort level (LDL) and hearing threshold (HT) of the subjects and investigated their self-reported symptoms. We compared the demographic characteristics, loudness discomfort level, and hearing threshold of the two groups and analyzed the self-reported symptoms and audiological characteristics of hyperacusis. We considered 87 subjects, comprising 40 patients with hyperacusis and 47 healthy individuals. Among the hyperacusis patients, bilateral disease was predominant. Among them, 33 were females, 23 had hearing loss, and 20 had tinnitus. Patients are mainly in the 21-60 age group. Patients with hyperacusis had low discomfort thresholds at all frequencies except 500 Hz (P <= 0.05, mean LDL decreased by 6.14-1.37 dB HL for all frequencies). The incidences of feeling upset, pain, and anxiety or fear were 95%, 65%, and 82.5%, respectively, in patients with hyperacusis. The severity of symptoms varies between patients with hyperacusis and healthy individuals. A combination of LDL measurements and self-reported symptom surveys allows for an accurate and comprehensive assessment of hyperacusis.Trial registration: This study was retrospectively registered (TRN: ChiCTR2100047391) on June 13, 2021."
基金机构：Sichuan Province Administration of Traditional Chinese Medicine [2018KF019]; Doctoral Research Initiation Fund of Affiliated Hospital of Southwest Medical University 
基金资助正文："AcknowledgementsI wish to thank Yan Xiao, Jun-mei Pu and Lu Liu for advice on experimental design. Funding from the Sichuan Province Administration of Traditional Chinese Medicine (Grant No. 2018KF019) and the Doctoral Research Initiation Fund of Affiliated Hospital of Southwest Medical University (Grant No. 19028) is gratefully acknowledged."