Induced membrane technique combined with a retrograde intramedullary nail for the treatment of infected bone defects of the ankle

作者全名："Fu, Jingshu; Wang, Xiaohua; Wang, Shulin; Chen, Zenggang; Shen, Jie; Li, Zhengyun; Xie, Zhao"

作者地址："[Fu, Jingshu; Chen, Zenggang; Li, Zhengyun] Chongqing Med Univ, Banan Hosp, Dept Orthoped, Chongqing 401320, Peoples R China; [Wang, Xiaohua; Wang, Shulin; Shen, Jie; Xie, Zhao] Army Med Univ, Mil Med Univ 3, Natl & Reg United Engn Lab Tissue Engn, Dept Orthopaed,Affiliated Hosp 1, Chongqing 400038, Peoples R China"

通信作者："Li, ZY (通讯作者)，Chongqing Med Univ, Banan Hosp, Dept Orthoped, Chongqing 401320, Peoples R China.; Xie, Z (通讯作者)，Army Med Univ, Mil Med Univ 3, Natl & Reg United Engn Lab Tissue Engn, Dept Orthopaed,Affiliated Hosp 1, Chongqing 400038, Peoples R China."

来源：SCIENTIFIC REPORTS

ESI学科分类：Multidisciplinary

WOS号：WOS:000997547300068

JCR分区：Q1

影响因子：4.6

年份：2023

卷号：13

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："In this study, we treated infected ankle bone defects with the induced membrane two-stage technique. The ankle was fused with a retrograde intramedullary nail in the second stage, and the aim of this study was to observe the clinical effect. We retrospectively enrolled patients with infected bone defects of the ankle admitted to our hospital between July 2016 and July 2018. In the first stage, the ankle was temporarily stabilized with a locking plate, and antibiotic bone cement was used to fill the defects after debridement. In the second stage, the plate and cement were removed, the ankle was stabilized with a retrograde nail, and tibiotalar-calcaneal fusion was performed. Then, autologous bone was used to rebuild the defects. The infection control rate, fusion success rate and complications were observed. Fifteen patients were enrolled in the study with an average follow-up of 30 months. Among them, there were 11 males and 4 females. The average bone defect length after debridement was 5.3 cm (2.1-8.7 cm). Finally, 13 patients (86.6%) achieved bone union without recurrence of infection, and 2 patients experienced recurrence after bone grafting. The average ankle-hindfoot function score (AOFAS) increased from 29.75 +/- 4.37 to 81.06 +/- 4.72 at the last follow-up. The induced membrane technique combined with a retrograde intramedullary nail for the treatment of infected bone defects of the ankle after thorough debridement is an effective treatment method."

基金机构：National Natural Science Foundation of China [82202707]; Natural Science Foundation of Chongqing [cstc2021jcyj-msxmX0541]

基金资助正文："This work was supported by The National Natural Science Foundation of China (82202707); Natural Science Foundation of Chongqing, cstc2021jcyj-msxmX0541"