Visual impairment and blindness caused by retinal diseases: A nationwide register-based study

作者全名："Zhou, Chuandi; Li, Shu; Ye, Luyao; Chen, Chong; Liu, Shu; Yang, Hongxia; Zhuang, Peng; Liu, Zengye; Jiang, Hongwen; Han, Jing; Jiang, Yiping; Zhou, Liqin; Zhou, Xiyuan; Xiao, Jun; Zhang, Cangxia; Wen, Lihui; Lan, Changjun; Wang, Yuqing; Sun, Tao; Jiang, Li; Xie, Peipei; Chen, Fan; Liang, Ge; Fu, Dongdong; Zhang, Tianzi; Shi, Xuetao; Song, Zhengyu; Liu, Xinghong; Li, Shanshan; Li, Pengcheng; Xu, Xiangzhou; Wei, Qinfeng; Wang, Weibang; Huang, Xionggao; De, Zhen; Deng, Aijun; Ding, Lin; Pan, Xiuhong; Wen, Haiyan; Zhang, Zhongchen; Lv, Hongbin; Zhang, Jian; Tian, Xuemin; Deng, Zhen; Wang, Hua; Wang, Fang; Wang, Yu; Zhao, Hongchao; Fang, Yanhong; Wu, Yuyu; Wu, Yufeng; Shen, Nian; Li, Bo; Li, Xiaorong; Dai, Hong; Zhao, Naiqing; Sun, Xiaodong; Zheng, Zhi; Liu, Kun; Xu, Xun"

作者地址："[Zhou, Chuandi; Ye, Luyao; Chen, Chong; Sun, Xiaodong; Zheng, Zhi; Liu, Kun; Xu, Xun] Shanghai Jiao Tong Univ, Dept Ophthalmol, Shanghai Gen Hosp, Sch Med,Natl Clin Res Ctr Eye Dis,Shanghai Engn Ct, Shanghai, Peoples R China; [Li, Shu] Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Dept Nursing, Sch Med, Shanghai, Peoples R China; [Li, Shu] Binzhou Med Univ, Dept Ophthalmol, Yantai Affiliated Hosp, Yantai, Shandong, Peoples R China; [Yang, Hongxia] First Peoples Hosp Jinzhong, Dept Ophthalmol, Jinzhong, Liaoning, Peoples R China; [Zhuang, Peng] Fujian Med Univ, Zhangzhou Municipal Hosp Fujian Prov, Dept Ophthalmol, Zhangzhou Affiliated Hosp, Zhangzhou, Fujian, Peoples R China; [Liu, Zengye] Tianjin First Cent Hosp, Dept Ophthalmol, Tianjin, Peoples R China; [Jiang, Hongwen] First Peoples Hosp Kashgar, Dept Ophthalmol, Kashgar, Xinjiang Uighur, Peoples R China; [Han, Jing] Air Force Med Univ, Dept Ophthalmol, Affiliated Hosp 2, Xian, Shanxi, Peoples R China; [Jiang, Yiping] Gannan Med Univ, Dept Ophthalmol, Affiliated Hosp 1, Gannan, Jiangxi, Peoples R China; [Zhou, Liqin] Jiaxing Univ, Hosp Jiaxing 1, Dept Ophthalmol, Affiliated Hosp, Jiaxing, Zhejiang, Peoples R China; [Zhou, Xiyuan] Chongqing Med Univ, Dept Ophthalmol, Affiliated Hosp 2, Chongqing, Peoples R China; [Xiao, Jun] Second Hosp Jilin Univ, Dept Ophthalmol, Changchun, Jilin, Peoples R China; [Zhang, Cangxia] Cangzhou Hosp Integrated TCM WM Hebei, Dept Ophthalmol, Cangzhou, Hebei, Peoples R China; [Wen, Lihui] Second Peoples Hosp Guilin, Dept Ophthalmol, Guilin, Guangxi, Peoples R China; [Lan, Changjun] North Sichuan Med Coll, Affiliated Hosp, Dept Ophthalmol, Nanchong, Sichuan, Peoples R China; [Jiang, Yiping] Jiamusi Univ, Dept Ophthalmol, Affiliated Hosp 1, Jiamusi, Heilongjiang, Peoples R China; [Sun, Tao] Yancheng City 1 Peoples Hosp, Dept Ophthalmol, Yancheng, Jiangsu, Peoples R China; [Jiang, Li] Benxi Cent Hosp, Dept Ophthalmol, Benxi, Liaoning, Peoples R China; [Xie, Peipei] 152 th Cent Hosp Peoples Liberat Army, Dept Ophthalmol, Pingdingshan, Henan, Peoples R China; [Chen, Fan] Anqing Municipal Hosp, Dept Ophthalmol, Anqing, Anhui, Peoples R China; [Liang, Ge] PLA Rocket Force Characterist Med Ctr, Dept Ophthalmol, Beijing, Peoples R China; [Fu, Dongdong] Peoples Hosp Zunyi City Bo Zhou Dist, Dept Ophthalmol, Zunyi, Guzhou, Peoples R China; [Zhang, Tianzi] Inner Mongolia Minzu Univ, Dept Ophthalmol, Affiliated Hosp, Tongliao, Inner Mongolia, Peoples R China; [Shi, Xuetao] Puer City Peoples Hosp, Dept Ophthalmol, Puer, Yunnan, Peoples R China; [Song, Zhengyu] Shanghai Univ Tradit Chinese Med, Shuguang Hosp, Dept Ophthalmol, Shanghai, Peoples R China; [Liu, Xinghong] Cent Hosp Shaoyang, Dept Ophthalmol, Shaoyang, Hunan, Peoples R China; [Li, Shanshan] WorkersHosp Jinchuan Grp Co Ltd, Dept Ophthalmol, Jinchang, Gansu, Peoples R China; [Li, Pengcheng] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Ophthalmol, Wuhan, Hubei, Peoples R China; [Sun, Xiaodong] Huizhou First Hosp, Dept Ophthalmol, Huizhou, Guangdong, Peoples R China; [Wei, Qinfeng] Second Peoples Hosp Xining, Dept Ophthalmol, Xining, Qinghai, Peoples R China; [Wang, Weibang] Ningxia Med Sch, Peoples Hosp Yinchuan 1, Dept Ophthalmol, Affiliated Hosp 2, Yinchuan, Ningxia Hui Aut, Peoples R China; [Huang, Xionggao] Hainan Med Univ, Hainan Gen Hosp, Dept Ophthalmol, Hainan Affiliated Hosp, Haikou, Hainan, Peoples R China; [De, Zhen] Shigatse Peoples Hosp, Dept Ophthalmol, Shigatse, Tibet Autonomou, Peoples R China; [Deng, Aijun] Weifang Med Sch, Dept Ophthalmol, Affiliated Hosp, Weifang, Shandong, Peoples R China; [Ding, Lin] Peoples Hosp Xinjiang Uygur Autonomous Reg, Dept Ophthalmol, Urumqi, Xinjiang Uygur, Peoples R China; [Pan, Xiuhong] Yuncheng Eye Hosp, Yuncheng, Shanxi, Peoples R China; [Wen, Haiyan] Peoples Hosp Jilin City, Dept Ophthalmol, Jilin, Jilin, Peoples R China; [Zhang, Zhongchen] Hebei Yanda Hosp, Dept Ophthalmol, Langfang, Hebei, Peoples R China; [Lv, Hongbin] Southwest Med Univ, Dept Ophthalmol, Affiliated Hosp, Luzhou 646000, Sichuan, Peoples R China; [Zhang, Jian] Shaanxi Prov Peoples Hosp, Dept Ophthalmol, Xian, Shanxi, Peoples R China; [Tian, Xuemin] 988 th Hosp Joint Logist Support Force Chinese Peo, Dept Ophthalmol, Kaifeng, Henan, Peoples R China; [Deng, Zhen] First Peoples Hosp Linping Dist, Dept Ophthalmol, Hangzhou, Zhejiang, Peoples R China; [Wang, Hua] First Peoples Hosp Lianyungang, Dept Ophthalmol, Lianyungang, Jiangsu, Peoples R China; [Wang, Fang] Guizhou Univ Tradit Chinese Med, Dept Ophthalmol, Affiliated Hosp 2, Guiyang, Guizhou, Peoples R China; [Wang, Yu] Fushun Ophthalmopathy Hosp, Fushun, Liaoning, Peoples R China; [Zhao, Hongchao] Peoples Hosp Yuxi City, Dept Ophthalmol, Yuxi, Yunnan, Peoples R China; [Fang, Yanhong] Jiangjin Cent Hosp, Dept Ophthalmol, Chongqing, Peoples R China; [Wu, Yuyu] Fujian Med Univ, Dept Ophthalmol, Affiliated Hosp 2, Quanzhou, Fujian, Peoples R China; [Wu, Yufeng] Qingyang Peoples Hosp, Dept Ophthalmol, Qingyang, Gansu, Peoples R China; [Shen, Nian] Liuzhou Peoples Hosp, Dept Ophthalmol, Liuzhou, Guangxi Zhuang, Peoples R China; [Li, Xiaorong] Tianjin Med Univ, Sch Optometry, Dept Ophthalmol, Eye Hosp, Tianjin, Peoples R China; [Li, Xiaorong] Eye Inst, Tianjin, Peoples R China; [Dai, Hong] Beijing Hosp, Dept Ophthalmol, Beijing, Peoples R China; [Zhao, Naiqing] Fudan Univ, Sch Publ Hlth, Dept Biostat, Shanghai, Peoples R China; [Zheng, Zhi; Liu, Kun; Xu, Xun] Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Dept Ophthalmol, Sch Med,Natl Clin Res Ctr Eye Dis,Shanghai Engn Ct, 100 Haining Rd, Shanghai, Peoples R China"

通信作者："Zheng, Z; Liu, K; Xu, X (通讯作者)，Shanghai Jiao Tong Univ, Shanghai Gen Hosp, Dept Ophthalmol, Sch Med,Natl Clin Res Ctr Eye Dis,Shanghai Engn Ct, 100 Haining Rd, Shanghai, Peoples R China."

来源：JOURNAL OF GLOBAL HEALTH

ESI学科分类：SOCIAL SCIENCES, GENERAL

WOS号：WOS:001104427100001

JCR分区：Q1

影响因子：7.2

年份：2023

卷号：13

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："Background Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal to inform optimal eye health care plan-ning and allocation of medical resources. The purpose of this study is to describe the propor-tion of visual impairment and blindness caused by major ret-inal diseases in China. Methods A nationwide reg-ister-based study of vitreoret-inal disease covering all 31 provinces (51 treating centres) of mainland China. A total of 28 320 adults diagnosed with retinal diseases were included. Participants underwent stan-dardised ocular examinations, which included best-corrected visual acuity (BCVA), dilat-ed-fundus assessments, and optical coherence tomography. Visual impairment and blind-ness are defined using BCVA according to the World Health Organization (WHO) (visual impairment: <20/63->= 20/400; blindness: <20/400) and the United States (visual impair-ment: <20/40->= 20/200; blind-ness: <20/200) definitions. The risk factors of vision loss were explored by logistic regression analyses.Results Based on the WHO definitions, the proportions for unilateral visual impairment and blind-ness were 46% and 18%, respectively, whereas those for bilateral visual impairment and blindness were 31% and 3.3%, respectively. Diabetic retinopathy (DR) accounts for the largest proportion of pa-tients with visual impairment (unilateral visual impairment: 32%, bilateral visual impairment: 60%) and blindness (unilateral blindness: 35%; bilateral blindness: 64%). Other retinal diseases that con-tributed significantly to vision loss included age-related macular degeneration, myopic maculopathy, retinal vein occlusion, and rhegmatogenous retinal detachment and other macular diseases. Women (bilateral vision loss: P = 0.011), aged patients (unilateral vision loss: 45-64 years: P < 0.001, >= 65 years: P < 0.001; bilateral vision loss: 45-64 years: P = 0.003, >= 65 years: P < 0.001 (reference: 18-44 years)) and those from Midwest China (unilateral and bilateral vision loss: both P < 0.001) were more likely to suffer from vision loss.Conclusions Retinal disorders cause substantial visual burden among patients with retinal diseases in China. DR, the predominant retinal disease, is accountable for the most prevalent visual disabilities. Bet-ter control of diabetes and scaled-up screenings are warranted to prevent DR. Specific attention should be paid to women, aged patients, and less developed regions."

基金机构：National Key R&D Program of China [2019YFC0840607]; National Science and Technology Major Project of China [2017ZX09304010]

基金资助正文："This research is funded by National Key R & D Program of China (2019YFC0840607) , National Science and Technology Major Project of China (2017ZX09304010) . The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.r Funding: This research is funded by National Key R&D Program of China (2019YFC0840607) , National Science and Technology Major Project of China (2017ZX09304010) . The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."