The Incidence of Long-Term Cholangitis after Endoscopic Papillary Balloon Dilation Versus Endoscopic Sphincterotomy: a Meta-analysis

作者全名："Xiang, Zhi-yong; Li, Chun-mei; Deng, Yi; Tan, Ye"

作者地址："[Xiang, Zhi-yong; Li, Chun-mei; Deng, Yi; Tan, Ye] Chongqing Med Univ, Affiliated Hosp 3, Gener Hosp, Dept Hepatobiliary & Pancreat Surg, Chongqing 401120, Peoples R China"

通信作者："Tan, Y (通讯作者)，Chongqing Med Univ, Affiliated Hosp 3, Gener Hosp, Dept Hepatobiliary & Pancreat Surg, Chongqing 401120, Peoples R China."

来源：INDIAN JOURNAL OF SURGERY

ESI学科分类：CLINICAL MEDICINE

WOS号：WOS:001109997900001

JCR分区：Q4

影响因子：0.4

年份：2023

卷号：　

期号：　

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结束页：　

文献类型：Review; Early Access

关键词：Endoscopic papillary balloon dilation; Endoscopic sphincterotomy; Long-term; Cholangitis

摘要："The objective of this study was to assess the long-term incidence of cholangitis after endoscopic papillary balloon dilation (EPBD) and endoscopic sphincterotomy (EST) using a meta-analysis. Until December, 2022, published randomized controlled trials searched systematically from PubMed, Embase, and Cochrane Library were assessed for the comparison of EPBD and EST. The statistical calculation was performed by RevMan 5.1. A P < 0.05 was considered statistical difference. In total, 6 studies containing 931 patients were screened for review. Of the patients being analyzed, 444 were treated with EPBD and 487 with EST. The long-term incidence of cholangitis decreased significantly in EPBD group compared with EST (relative risk (RR) = 0.48, 95%CI: 0.25 to 0.92, P = 0.03), while clearance in 1 session ERCP was of no difference (RR = 0.98, 95%CI: 0.89 to 1.07, P = 0.65). Subgroup analyses demonstrated that incidence of cholangitis did not differ significantly regarding dilation diameter, time, or pressure. However, as for the most common adverse reaction, post-ERCP pancreatitis (PEP) occurred more often in EPBD group compared with EST (relative risk (RR) = 2.17, 95%CI: 1.30 to 3.61, P = 0.003). In conclusion, the long-term incidence of cholangitis was significantly lower with EPBD compared to EST. With similar efficacy of bile duct clearance in 1 session, EPBD gave rise to less stone recurrence, yet higher PEP incidence."

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