Endobronchial optical coherence tomography helps to estimate the cartilage damage of the central airway in TBTB patients

作者全名："Zong, Kaican; Liu, Bin; Li, Shiying; Li, Yishi; Guo, Shuliang"

作者地址："[Zong, Kaican; Liu, Bin; Li, Yishi; Guo, Shuliang] Chongqing Med Univ, Affiliated Hosp 1, Dept Resp Med, Chongqing, Peoples R China; [Zong, Kaican] Chongqing Univ Technol, Dept Resp Med, Cent Hosp, Chongqing, Peoples R China; [Li, Shiying] Chongqing Med Univ, Affiliated Hosp 2, Inst Viral Hepatitis, Dept Infect Dis,Key Lab Mol Biol Infect Dis,Minist, Chongqing, Peoples R China"

通信作者："Li, YS; Guo, SL (通讯作者)，Chongqing Med Univ, Affiliated Hosp 1, Dept Resp Med, Chongqing, Peoples R China."

来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

ESI学科分类：MICROBIOLOGY

WOS号：WOS:001125896400001

JCR分区：Q2

影响因子：5.7

年份：2023

卷号：13

期号：　

开始页：　

结束页：　

文献类型：Article

关键词：endobronchial optical coherence tomography; tracheobronchial tuberculosis; cartilage; central airway; airway wall

摘要："PurposeAt present, there are few examination methods used to evaluate tracheobronchial cartilage damage. In our study, we explored whether endobronchial optical coherence tomography (EB-OCT) can be used to estimate central airway cartilage damage in tracheobronchial tuberculosis (TBTB) patients.MethodsIn our study, we used the OCTICS Imaging system to perform EB-OCT scanning for TBTB patients. The thickness of the central airway wall and cartilage was measured by the OCTICS software system workstation.ResultsThere were 102 TBTB patients included in our study cohort. Their EB-OCT images of the central airway cartilage showed that abnormal cartilage manifests as thinning of the cartilage, cartilage damage, cartilage destruction, and even cartilage deficiency. The cartilage morphology becomes irregular and discontinuous. Some parts of the cartilage become brighter in grayscale. The intima of the cartilage is thickened and discontinuous, and the boundary with submucosa and mucosa is unclear.ConclusionOur study conducted EB-OCT examination of the central airway cartilage of TBTB patients in vivo for the first time. EB-OCT helps to estimate the cartilage damage of the central airway in TBTB patients to some extent."

基金机构：Science and Technology Research Program of Chongqing Municipal Education Commission [KJQN202301154]; Future Medical Youth Innovation Team Development Support Plan of Chongqing Medical University [W0119]; Famous experts and teachers of the Chongqing Talents Program

基金资助正文："The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was supported by the Science and Technology Research Program of Chongqing Municipal Education Commission (Grant No.KJQN202301154) (KZ) and the Future Medical Youth Innovation Team Development Support Plan of Chongqing Medical University(W0119) (YL). This study was also supported by famous experts and teachers of the Chongqing Talents Program (SG)."