Changes in oscillatory patterns of microstate sequence in patients with first-episode psychosis

作者全名："Zhou, Dong-Dong; Li, Hong-Zhi; Wang, Wo; Kuang, Li"

作者地址："[Zhou, Dong-Dong; Li, Hong-Zhi; Wang, Wo; Kuang, Li] Chongqing Med Univ, Univ Town Hosp, Mental Hlth Ctr, Chongqing, Peoples R China; [Kuang, Li] Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, Chongqing, Peoples R China"

通信作者："Zhou, DD; Kuang, L (通讯作者)，Chongqing Med Univ, Univ Town Hosp, Mental Hlth Ctr, Chongqing, Peoples R China.; Kuang, L (通讯作者)，Chongqing Med Univ, Dept Psychiat, Affiliated Hosp 1, Chongqing, Peoples R China."

来源：SCIENTIFIC DATA

ESI学科分类：Multidisciplinary

WOS号：WOS:001137119200004

JCR分区：Q1

影响因子：9.8

年份：2024

卷号：11

期号：1

开始页：　

结束页：　

文献类型：Article

关键词：　

摘要："We aimed to utilize chaos game representation (CGR) for the investigation of microstate sequences and explore its potential as neurobiomarkers for psychiatric disorders. We applied our proposed method to a public dataset including 82 patients with first-episode psychosis (FEP) and 61 control subjects. Two time series were constructed: one using the microstate spacing distance in CGR and the other using complex numbers representing the microstate coordinates in CGR. Power spectral features of both time series and frequency matrix CGR (FCGR) were compared between groups and employed in a machine learning application. The four canonical microstates (A, B, C, and D) were identified using both shared and separate templates. Our results showed the microstate oscillatory pattern exhibited alterations in the FEP group. Using oscillatory features improved machine learning performance compared with classical features and FCGR. This study opens up new avenues for exploring the use of CGR in analyzing EEG microstate sequences. Features derived from microstate sequence CGR offer fine-grained neurobiomarkers for psychiatric disorders."

基金机构：This work was supported by a grant from the Chongqing medical scientific research youth project (Joint project of Chongqing Health Commission and Science and Technology Bureau) (2023QNXM050). [2023QNXM050]; Chongqing medical scientific research youth project (Joint project of Chongqing Health Commission and Science and Technology Bureau)

基金资助正文：This work was supported by a grant from the Chongqing medical scientific research youth project (Joint project of Chongqing Health Commission and Science and Technology Bureau) (2023QNXM050).